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Health and Environment-wide Associations based on Large population Surveys

Objective

Assessing individual exposure to environmental stressors and predicting health outcomes implies that both environmental exposures and epi/genetic variations are reliably measured simultaneously. HEALS (Health and Environment-wide Associations based on Large population Surveys) brings together in an innovative approach a comprehensive array of novel technologies, data analysis and modeling tools that support efficiently exposome studies. The general objective of HEALS is the refinement of an integrated methodology and the application of the corresponding analytical and computational tools for performing environment-wide association studies in support of EU-wide environment and health assessments. The exposome represents the totality of exposures from conception onwards, simultaneously identifying, characterizing and quantifying the exogenous and endogenous exposures and modifiable risk factors that predispose to and predict diseases throughout a person’s life span. The HEALS approach brings together and organizes environmental, socio-economic, exposure, biomarker and health effect data; in addition, it includes all the procedures and computational sequences necessary for applying advanced bioinformatics coupling thus effective data mining, biological and exposure modeling so as to ensure that environmental exposure-health associations are studied comprehensively. The overall approach will be verified and refined in a series of population studies across Europe including twin cohorts, tackling different levels of environmental exposure, age windows of exposure, and socio-economic and genetic variability. The HEALS approach will be applied in a pilot environment and health examination survey of children including singletons and sets of twins with matched singletons (each twins pair having also a matched singleton) covering ten EU Member States (the EXHES Study). The lessons learned will be translated into scientific advice towards the development of protocols and guidelines for the setting up of a larger European environment and health examination survey.

Call for proposal

FP7-ENV-2013-two-stage
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Coordinator

UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6
Address
Place Jussieu 4
75252 Paris
France
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 116 061,11
Administrative Contact
Isabella Annesi-Maesano (Dr.)

Participants (35)

TEKNOLOGIAN TUTKIMUSKESKUS VTT

Participation ended

Finland
EU contribution
€ 424 694,10
Address
Tekniikantie 4 A
02044 VTT Espoo
Activity type
Research Organisations
Administrative Contact
Sami Nousiainen (Mr.)
ARISTOTELIO PANEPISTIMIO THESSALONIKIS
Greece
EU contribution
€ 994 803
Address
Kedea Building, Tritis Septemvriou, Aristotle Univ Campus
54636 Thessaloniki
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Georgia Petridou (Ms.)
INSTITUTE OF OCCUPATIONAL MEDICINE
United Kingdom
EU contribution
€ 458 239,30
Address
Research Avenue North, Riccarton 45
EH14 4AP Edinburgh
Activity type
Research Organisations
Administrative Contact
Susy Young (Mrs.)
UNIVERSITY OF STUTTGART
Germany
EU contribution
€ 477 656
Address
Keplerstrasse 7
70174 Stuttgart
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Martin Spengler (Mr.)
INSTITUT JOZEF STEFAN
Slovenia
EU contribution
€ 490 776,20
Address
Jamova 39
1000 Ljubljana
Activity type
Research Organisations
Administrative Contact
Jadran Lenarčič (Prof.)
UNIVERSITE PARIS DESCARTES
France
EU contribution
€ 522 296,20
Address
Rue De L Ecole De Medecine 12
75270 Paris Cedex 06
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Rosaly Datchi (Mrs.)
UNIVERSITY OF BRISTOL
United Kingdom
EU contribution
€ 284 231,47
Address
Beacon House Queens Road
BS8 1QU Bristol
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Audrey Michael (Mrs.)
ISTITUTO SUPERIORE DI SANITA
Italy
EU contribution
€ 580 719,20
Address
Viale Regina Elena 299
00161 Roma
Activity type
Research Organisations
Administrative Contact
Rosa Maria Martoccia (Dr.)
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 404 306
Address
Geschwister Scholl Platz 1
80539 Muenchen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Stephan Boese-O'reilly (Dr.)
INSTYTUT MEDYCYNY PRACY IMIENIA PROF. DRA MED. JERZEGO NOFERA W LODZI
Poland
EU contribution
€ 325 994
Address
Ul Sw Teresy Od Dzieciatka Jezus 8
91 348 Lodz
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kamila Szczesniak (Ms.)
TEKNOLOGIAN TUTKIMUSKESKUS VTT OY
Finland
Address
Tekniikantie 21
02150 Espoo
Activity type
Research Organisations
Administrative Contact
Sami Nousiainen (Mr.)
THE UNIVERSITY OF MANCHESTER
United Kingdom
EU contribution
€ 275 576,38
Address
Oxford Road
M13 9PL Manchester
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Claire Faichnie (Ms.)
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO
Netherlands
EU contribution
€ 638 669,80
Address
Anna Van Buerenplein 1
2595 DA Den Haag
Activity type
Research Organisations
Administrative Contact
Rianda Gerritsen-Ebben (Dr.)
Food and Environment Research Agency

Participation ended

United Kingdom
EU contribution
€ 342 021,80
Address
Area 1A, Nobel House, Smith Square 17
SW1P 3JR London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Adrian Charlton (Dr.)
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 450 437,40
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
Maria Angeles Lopez Vazquez (Ms.)
PANEPISTIMIO DYTIKIS MAKEDONIAS
Greece
EU contribution
€ 317 862,50
Address
Parko Agiou Dimitriou 1
50100 Kozani
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Petros Patias (Prof.)
FUNDACIO PARC CIENTIFIC DE BARCELONA
Spain
EU contribution
€ 274 016,70
Address
Baldiri I Reixac 4
08028 Barcelona
Activity type
Research Organisations
Administrative Contact
Moises Tarte (Mr.)
INSTITUTO DE ENGENHARIA MECANICA

Participation ended

Portugal
EU contribution
€ 51 262,94
Address
Rua Rovisco Pais 1
1049 001 Lisboa
Activity type
Research Organisations
Administrative Contact
Eduardo De Oliveira Fernandes (Prof.)
OIKON DOO INSTITUT ZA PRIMIJENJENU EKOLOGIJU

Participation ended

Croatia
EU contribution
€ 133 549,27
Address
Trg Senjskih Uskoka 1-2
10020 Zagreb
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Zdravko Spiric (Dr.)
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
EU contribution
€ 285 500,70
Address
Piazzale Aldo Moro 7
00185 Roma
Activity type
Research Organisations
Administrative Contact
Donatella Spera (Ms.)
UNIVERSIDADE DO PORTO
Portugal
EU contribution
€ 336 698,80
Address
Praca Gomes Teixeira
4099 002 Porto
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Manuela Mota (Prof.)
"NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS"""
Greece
EU contribution
€ 447 565,40
Address
End Of Patriarchou Grigoriou E And 27 Neapoleos Street
15341 Agia Paraskevi
Activity type
Research Organisations
Administrative Contact
Euripides Papadopoulos (Mr.)
UNIVERSITAT ROVIRA I VIRGILI
Spain
EU contribution
€ 312 893,30
Address
Carrer De Escorxador
43003 Tarragona
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marta Schuhmacher (Prof.)
KLINIKUM DER UNIVERSITAET REGENSBURG.
Germany
EU contribution
€ 248 950
Address
Frans Josef Strauss Allee 11
93053 Regensburg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Geiger Elisabeth (Mrs.)
GENOMIC INVESTMENTS BV

Participation ended

Netherlands
EU contribution
€ 198 333
Address
Plesmanlaan 1D
2333 BZ Leiden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Pascal Berserik (Mr.)
KING'S COLLEGE LONDON
United Kingdom
EU contribution
€ 286 263,60
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Labbett (Mr.)
FOLKEHELSEINSTITUTTET
Norway
EU contribution
€ 61 668
Address
Lovisenberggata 8
0456 Oslo
Activity type
Research Organisations
Administrative Contact
Anina Saetre Bjoernhaug (Ms.)
SYDDANSK UNIVERSITET
Denmark
EU contribution
€ 61 668
Address
Campusvej 55
5230 Odense M
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ulla Iversen (Ms.)
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
United States
EU contribution
€ 75 000
Address
Franklin Street 1111, 12 Floor
94607 Oakland Ca
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Wendi Hayes (Ms.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 61 668
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Agneta Häggström (Ms.)
INEGI - INSTITUTO DE CIENCIA E INOVACAO EM ENGENHARIA MECANICA E ENGENHARIA INDUSTRIAL
Portugal
EU contribution
€ 207 590,55
Address
Rua Dr Roberto Frias 400
4200 465 Porto
Activity type
Research Organisations
Administrative Contact
Sérgio Cunha (Dr.)
FERA SCIENCE LIMITED
United Kingdom
Address
65 Gresham Street
EC2V 7NQ London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Christina Steveni (Dr.)
ZELENA INFRASTRUKTURA DRUSTVO S OGRANICENOM ODGOVORNOSCU ZA ZASTITU OKOLISA I PROSTORNO UREDENJE
Croatia
EU contribution
€ 192 233,13
Address
Fallerovo Setaliste 22
10000 Zagreb
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Zdravko Spiric (Prof.)
AARHUS UNIVERSITET
Denmark
EU contribution
€ 175 277,93
Address
Nordre Ringgade 1
8000 Aarhus C
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Lizi Keinicke Christensen (Mrs.)
GenomeScan B.V.
Netherlands
Address
Plesmanlaan 1D
2333 BZ Leiden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Cornelis Van Den Berg (Mr.)