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Methods for high-throughput glycoproteomic analysis

Project information

Grant agreement ID: 324400

Status

Closed project

  • Start date

    1 November 2013

  • End date

    31 October 2017

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 1 818 077,90

  • EU contribution

    € 1 818 077,90

Coordinated by:

SVEUCILISTE U RIJECI

Croatia

Objective

The main aim of the HTP-GlycoMet proposal is to develop technologies, which will enable high-throughput analysis of glycosylation of individual proteins from body fluids and cell membranes and apply them to understand some key processes in immunity and infections. Glycan analysis is extremely demanding from both technological and conceptual aspect and (beside one study performed by partners in this proposal) large-scale studies of glycosylation of individual proteins were not attempted previously. However, we are confident that by successfully combining complementary expertise in the (i) production of specialised monolithic chromatographic tools for high-throughput fractionation of complex biological fluids (BIA-SEP), (ii) purification of proteins from body fluids and membrane proteins (UNI-RI), (iii) high-throughput glycomic analysis by use of chromatography (Genos) and multiplexed capillary gel electrophoresis (MPI) and (iv) expertise in the field of viral immunology (MEDRI) we can achieve significant progress in this direction. All our partners are recognized leaders who already made significant progress beyond the state of the art in their respective fields. Through HTP-GlycoMet project we will organise secondments on all levels (MER, ER, ESR) to capitalize on synergistic effects of this interdisciplinary and transnational collaboration. In addition to the generation of new knowledge and the development of new innovative technologies, we will also achieve significant transfer of knowhow between academic and industrial partners. Our SME partners also expect to develop new lines of products and services through the HTP-GlycoMet programme, but also through future collaboration with HTP-GlycoMet partners beyond the lifetime of this project.

Coordinator

SVEUCILISTE U RIJECI

Address

Trg Brace Mazuranica 10
51000 Rijeka

Croatia

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 329 349,54

Administrative Contact

Djuro Josic (Prof.)

Participants (4)

BIA SEPARATIONS DOO

Slovenia

EU Contribution

€ 273 317,14

GENOS DOO ZA VJESTACENJE I ANALIZU

Croatia

EU Contribution

€ 560 256,86

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

Germany

EU Contribution

€ 338 055,63

SVEUCILISTE U RIJECI, MEDICINSKI FAKULTET

Croatia

EU Contribution

€ 317 098,73

Project information

Grant agreement ID: 324400

Status

Closed project

  • Start date

    1 November 2013

  • End date

    31 October 2017

Funded under:

FP7-PEOPLE

  • Overall budget:

    € 1 818 077,90

  • EU contribution

    € 1 818 077,90

Coordinated by:

SVEUCILISTE U RIJECI

Croatia