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Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior

Objective

Emerging evidence indicates that the gut microbiome contributes to our ability to extract energy from the diet and influences development and function of the immune, endocrine and nervous systems, which regulate energy balance and behaviour. This has led to hypothesize that developing microbiome-based dietary interventions can be cost-effective measures to prevent diet-related and behavioural disorders. Yet this approach is restricted in practice by a lack of understanding of the specific species that contribute to these disorders and their interactions with host and lifestyle determinants. To progress beyond the state of the art, the MyNewGut proposal aims to: (1) shed light on the contribution of the human microbiome to nutrient metabolism and energy expenditure; (2) identify microbiome-related features that contribute to or predict obesity and associated disorders in human epidemiological studies; (3) understand how the microbiome is influenced by environmental factors and its role in brain and immune development and function in humans; and (4) provide proof-of-concept of the disease risk-reduction potential of dietary intervention with new foods/ingredients targeting the gut microbiome in humans. To this end, a translational multidisciplinary research strategy will be developed, combining experts in omic-technologies and all other scientific disciplines required. Consequently, the MyNewGut proposal will contribute to developing new approaches to prevent diet-related diseases (metabolic syndrome and obesity) and behavioural disorders through lifestyle changes, intake of pro- and prebiotics and semi-personalised and innovative food products. This will ultimately contribute to increasing the competitiveness of the European food industry and provide consumers with reliable claims on foods. Results will also help inform new strategies on public health, support EU legislation and improve the position of the EU in the field of food-related disease prevention.

Field of science

  • /medical and health sciences/health sciences/public and environmental health

Call for proposal

FP7-KBBE-2013-7-single-stage
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Address
Calle Serrano 117
28006 Madrid
Spain
Activity type
Research Organisations
EU contribution
€ 1 713 293
Administrative Contact
María ángeles López Vázquez (Ms.)

Participants (29)

ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italy
EU contribution
€ 1 002 940
Address
Via Zamboni 33
40126 Bologna
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Rossana Bartone (Dr.)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland
EU contribution
€ 893 194
Address
Western Road
T12 YN60 Cork
Activity type
Higher or Secondary Education Establishments
Administrative Contact
David O'connell (Dr.)
KOBENHAVNS UNIVERSITET
Denmark
EU contribution
€ 548 994
Address
Norregade 10
1165 Kobenhavn
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Bjarne Friis Ploumark (Mr.)
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France
EU contribution
€ 497 914
Address
Rue De L'universite 147
75338 Paris Cedex 07
Activity type
Research Organisations
Administrative Contact
Maryse Blin (Mrs.)
UNIVERSITE CATHOLIQUE DE LOUVAIN
Belgium
EU contribution
€ 450 005
Address
Place De L Universite 1
1348 Louvain La Neuve
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Nathalie Delzenne (Prof.)
TECHNISCHE UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 451 550
Address
Arcisstrasse 21
80333 Muenchen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Dirk Haller (Prof.)
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO
Netherlands
EU contribution
€ 441 926
Address
Anna Van Buerenplein 1
2595 DA Den Haag
Activity type
Research Organisations
Administrative Contact
Marco Jaspers (Dr.)
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
EU contribution
€ 382 925
Address
Meibergdreef 15
1105AZ Amsterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Edwin Groenewegen Van Wijk (Mr.)
KLINIKUM DER UNIVERSITAET REGENSBURG
Germany
EU contribution
€ 315 573
Address
Frans Josef Strauss Allee 11
93053 Regensburg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Geiger Elisabeth (Ms.)
THE UNIVERSITY OF READING
United Kingdom
EU contribution
€ 266 403
Address
Whiteknights Campus Whiteknights House
RG6 6AH Reading
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mark Rodgers (Mr.)
MEDIZINISCHE UNIVERSITAT GRAZ
Austria
EU contribution
€ 224 756
Address
Auenbruggerplatz 2
8036 Graz
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kristina Kofler (Dr.)
LEIBNIZ-INSTITUT FUR PRAVENTIONSFORSCHUNG UND EPIDEMIOLOGIE - BIPS GMBH
Germany
EU contribution
€ 194 439
Address
Achterstrasse 30
28359 Bremen
Activity type
Other
Administrative Contact
Cornelia Wiedemeyer (Mrs.)
UNIVERSIDAD DE GRANADA
Spain
EU contribution
€ 150 900
Address
Cuesta Del Hospicio Sn
18071 Granada
Activity type
Higher or Secondary Education Establishments
Administrative Contact
María D. Suárez Ortega (Prof.)
INSTITUTE FOR FOOD TECHNOLOGY OF NOVI SAD
Serbia
EU contribution
€ 69 840
Address
Bulevar Cara Lazara 1
21000 Novi Sad
Activity type
Research Organisations
Administrative Contact
Nebojsa Ilic (Dr.)
EUROPEAN FOOD INFORMATION COUNCIL
Belgium
EU contribution
€ 281 340
Address
Rue Des Deux Eglises 14
1000 Bruxelles
Activity type
Other
Administrative Contact
Frédéric Goffard (Mr.)
STICHTING EFFOST
Netherlands
EU contribution
€ 70 000
Address
Nieuwe Kanaal 9 A
6709 PA Wageningen
Activity type
Research Organisations
Administrative Contact
Wilma Methorst (Ms.)
ICC-INTERNATIONAL ASSOCATION FOR CEREAL SCIENCE AND TECHNOLOGY
Austria
EU contribution
€ 110 800
Address
Marxergasse 2
1030 Wien
Activity type
Research Organisations
Administrative Contact
Roland Poms (Dr.)
CARGILL HAUBOURDIN SAS
France
EU contribution
€ 217 364
Address
Rue Du Marechal Joffre 7
59482 Haubourdin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Douwina Bosscher (Dr.)
BARILLA G. E R. FRATELLI SPA
Italy
EU contribution
€ 149 930
Address
Via Mantova 166
43122 Parma
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Paola Carnevali (Dr.)
LALLEMAND SAS
France
EU contribution
€ 66 240
Address
Rue Des Briquetiers 19
31700 Blagnac
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Thomas Tompkins (Dr.)
CORPORACION ALIMENTARIA PENASANTA - CAPSA
Spain
EU contribution
€ 200 562
Address
Sierra De Granda S/n
33119 Siero Granda
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Gonzalez Madera (Mrs.)
ALIMENTARY HEALTH LTD
Ireland
EU contribution
€ 91 600
Address
Kinsale Road Building 2800 Cork Airport Business Park
N/A Passage West, Co. Cork
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jennifer Roper (Dr.)
LOMAN FOOD CONSULTING BV
Netherlands
EU contribution
€ 155 625
Address
Lombardije 44
3524 KW Utrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Stoffer Loman (Dr.)
AKCIONARSKO DRUSTVO MLEKARA SUBOTICA
Serbia
EU contribution
€ 25 155
Address
Tolminska 10
Subotica
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Nurgin Memisi (Dr.)
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
Australia
Address
Clunies Ross Street Csiro Black Mountain Science And Innovation Park
2601 Acton Act
Activity type
Research Organisations
Administrative Contact
Lockett Trevor (Dr.)
BAYLOR COLLEGE OF MEDICINE
United States
Address
One Baylor Plaza T119
77030 Houston Tx
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Joseph Petrosino (Prof.)
UNIVERSITY OF MICHIGAN THE REGENTS OF THE UNIVERSITY OF MICHIGAN
United States
Address
South Street 3003 1068
46109 1274 Ann Arbor
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Xiaoxia Lin (Prof.)
THE UNIVERSITY OF AUCKLAND
New Zealand
Address
Princes Street 24
1010 Auckland
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Rinki Murphy (Dr.)
Queen's University at Kingston
Canada
Address
University Avenue 99
K7L 3N6 Kingston
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Karina Mcinnis (Ms.)