Obiettivo The global chemical industry is transitioning from petrochemical production processes to bio-based production processes. This transition creates a clear market need for technologies that reduce the development time and cost of cell factories. PROMYS will develop, validate and implement a novel synthetic biology platform technology termed ligand responsive regulation and selection systems. Ligand responsive regulation and selection systems are biological devices that integrate biological sensing modules, within larger regulatory networks to control cellular programs. This technology will drastically accelerate the construction, optimization and performance of cell factories by enabling industrial users to impose non-natural objectives on the engineered cell factory. PROMYS will address three major challenges in metabolic engineering that limit the development of new cell factories:1) Synthetic pathway construction2) Cell factory optimization3) Control of populations during fermentationLigand responsive regulation and selection systems will directly couple the presence of a desired chemical product or flux state within a cell, to the survival of the cell. As such, they allow the in vivo identification of the needle (e.g. functional pathway or optimized cell factories) in a haystack (e.g. large libraries). In addition, the technology developed in PROMYS will be applied to deliver increased fermentation yields by continuously selecting for high yielding cell factories within the fermentation population.PROMYS is industry driven and designed such that the expected innovations of each work package have a direct commercialization partner, which is willing to commit the necessary resources to develop commercial products from the innovation. Campo scientifico engineering and technologyindustrial biotechnologymetabolic engineeringnatural sciencesbiological sciencessynthetic biologyengineering and technologyindustrial biotechnologybioprocessing technologiesfermentation Programma(i) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Argomento(i) KBBE.2013.3.6-02 - Synthetic Biology towards applications Invito a presentare proposte FP7-KBBE-2013-7-single-stage Vedi altri progetti per questo bando Meccanismo di finanziamento CP-TP - Collaborative Project targeted to a special group (such as SMEs) Coordinatore DANMARKS TEKNISKE UNIVERSITET Contributo UE € 2 312 890,00 Indirizzo ANKER ENGELUNDS VEJ 101 2800 Kongens Lyngby Danimarca Mostra sulla mappa Regione Danmark Hovedstaden Københavns omegn Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Birte Rasmussen Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (6) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto BACMINE SL Spagna Contributo UE € 813 471,00 Indirizzo CALLE ISAAC NEWTON 2 PARQUE 28760 TRES CANTOS Mostra sulla mappa Regione Comunidad de Madrid Comunidad de Madrid Madrid Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Pablo Pomposiello Miravent (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Costo totale Nessun dato TECHNISCHE UNIVERSITAT DARMSTADT Germania Contributo UE € 904 418,00 Indirizzo KAROLINENPLATZ 5 64289 Darmstadt Mostra sulla mappa Regione Hessen Darmstadt Darmstadt, Kreisfreie Stadt Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Melanie Meermann-Zimmermann (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato RIJKSUNIVERSITEIT GRONINGEN Paesi Bassi Contributo UE € 1 004 400,00 Indirizzo Broerstraat 5 9712CP Groningen Mostra sulla mappa Regione Noord-Nederland Groningen Overig Groningen Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Dick Veldhuis (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato THE UNIVERSITY OF WARWICK Regno Unito Contributo UE € 722 423,00 Indirizzo Kirby Corner Road - University House CV4 8UW Coventry Mostra sulla mappa Regione West Midlands (England) West Midlands Coventry Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Peter Hedges (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato EVOLVA AG Svizzera Contributo UE € 712 800,00 Indirizzo DUGGINGERSTRASSE 23 4153 Reinach Mostra sulla mappa Regione Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Landschaft Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Michael Naesby (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato BIOSYNTIA APS Danimarca Contributo UE € 718 000,00 Indirizzo KOGLE ALLE 6 2970 Horsholm Mostra sulla mappa Regione Danmark Hovedstaden Nordsjælland Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Andreas Laustsen (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato