Obiettivo THIS WORK IS DIRECTED TO ANSWERING THREE MAIN QUESTIONS RELATED TO RADIATION CARCINOGENESIS IN THE THYROID. WHAT IS THE QUANTITATIVE RELATIONSHIP BETWEEN LOW DOSE RADIATION AND TUMOUR DEVELOPMENT. WHAT IS THE ROLE OF THE GROWTH STIMULATORY EFFECT OF TSH ON TUMOUR DEVELOPMENT. WHAT IS THE VALUE OF TSH SUPPRESSION IN THE PREVENTION OF RADIATION INDUCED THYROID TUMOURS. The results of a study of the rate of onset of focal hyperplasias (FH) and of adenomas (A) in the thyroid after a single dose of radiation followed by prolonged goitrogen therapy were of considerable interest. The study showed that the FH numbers increased linearly with time after radiation, but that A numbers initially increased more slowly and later increased more rapidly. The FH size profile remained almost unchanged with time, while the A profile showed a higher mode than FH and a much greater increase in higher diameter lesions with time. Both the change in absolute numbers and in diameter profile are consistent with a progression of FH to adenoma in the genesis of thyroid neoplasia.STUDIES OF THE MECHANISM AND PREVENTION OF LOW DOSE RADIATION CARCINOGENESIS OF THE THYROID. Programma(i) FP1-RADPROT 6C - Multiannual research and training programme (Euratom) in the field of radiation protection, 1985-1989 Argomento(i) Data not available Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore University of Wales College of Medicine Contributo UE Nessun dato Indirizzo Heath Park CF4 4XN Cardiff Regno Unito Mostra sulla mappa Costo totale Nessun dato
