Objective In InanoMOF, we aim to develop frontier Supramolecular and Nanochemistry methodologies for the synthesis of a novel class of structures via controlled assembly of nanoscale metal-organic frameworks (nanoMOFs) and inorganic nanoparticles (INPs). These methods will embody the premise that “controlled object-by-object nano-assembly is a ground-breaking approach to explore for producing systems of higher complexity with advanced functions”. The resulting hybrid nanoMOF@INPs will marry the unique properties of INPs (magnetism of iron oxide NPs and optics of Au NPs) to the functional porosity of MOFs.The first part of InanoMOF encompasses the design, synthesis-assembly and characterisation of nanoMOF@INPs - advanced MOF-based sorbents that incorporate the functionality of the INPs used: magnetically controlled movement, in vivo detectability, enhanced biocompatibility and porosity, pollutant removal, or controlled sorption/delivery. The second part of InanoMOF entails studying the physicochemical properties of the synthesised nanoMOF@INPs and ascertaining their utility as drug-delivery/theranostic systems and as magnetic sorbents for pollutant removal. Specifically, we will study their stability in working media and determine their capacities for drug or pollutant sorption/delivery capacities. As proof-of-concept, we will study their toxicity in vitro and in vivo; enhancement of their in vitro therapeutic efficacy; and their capacity to remove pollutants (in real water and gasoline/diesel fuel samples) via magnetic assistance.In InanoMOF we will endeavour to establish the synthetic bases for controlling the spatial ordering of nanoMOF crystals, whether alone or combined with other nanomaterials (e.g. INPs, graphene, etc.). We are confident that our work will ultimately enable researchers to create MOF-based composites having cooperative and synergistic properties and functions for myriad applications (e.g. heterogeneous catalysis, sensing and separation). Fields of science engineering and technologyenvironmental engineeringenergy and fuelsliquid fuelsengineering and technologynanotechnologynano-materialstwo-dimensional nanostructuresgrapheneengineering and technologymaterials engineeringcompositesnatural sciencesphysical sciencesopticsnatural scienceschemical sciencescatalysis Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-CG-2013-PE5 - ERC Consolidator Grant - Synthetic Chemistry and Materials Call for proposal ERC-2013-CoG See other projects for this call Funding Scheme ERC-CG - ERC Consolidator Grants Host institution FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA EU contribution € 1 942 664,98 Address CAMPUS DE LA UAB EDIFICI Q ICN2 08193 Cerdanyola Del Valles Spain See on map Region Este Cataluña Barcelona Activity type Research Organisations Principal investigator Daniel Maspoch Comamala (Prof.) Administrative Contact Marta Gonzalez Gomez (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Beneficiaries (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA Spain EU contribution € 1 942 664,98 Address CAMPUS DE LA UAB EDIFICI Q ICN2 08193 Cerdanyola Del Valles See on map Region Este Cataluña Barcelona Activity type Research Organisations Principal investigator Daniel Maspoch Comamala (Prof.) Administrative Contact Marta Gonzalez Gomez (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
