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Adaptations of the ATP synthesis machinery in bacteria and archaea to conditions of extreme<br/>energy limitation in the deep subsurface

Objectif

Microbes in the deep sub-seafloor have recently been found to survive under unprecedented conditions of extreme energy limitation. I aim to identify microbes in these deep subsurface communities with central energy metabolism that is adapted to these conditions. A combination of single-cell genomics and metagenomics will be used to identify members of the microbial community adapted to low energy flux by use of Na+-based chemiosmotic ATP synthesis. Following sequencing, genes encoding c subunits of the ATP synthase from the deep subsurface will be synthesized and expressed in E. coli to determine ATP synthase c ring stoichiometry. This project represents a novel approach to microbial ecology and physiology in energy-limited environments with a framework that combines state-of-the-art biogeochemistry, molecular microbial ecology, and biochemistry.

Appel à propositions

FP7-PEOPLE-2013-IIF
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Coordinateur

AARHUS UNIVERSITET
Contribution de l’UE
€ 221 154,60
Adresse
NORDRE RINGGADE 1
8000 Aarhus C
Danemark

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Région
Danmark Midtjylland Østjylland
Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Irene Hjortsberg (Mrs.)
Liens
Coût total
Aucune donnée