Obiettivo This project aims to build upon current developments in molecular imaging by developing a camera system and a tumour margin marker to be used in a first-in-human-trail. Molecular in vivo imaging is a fertile area which harbours a mix of expertise, state-of-art equipment and many different disciplines and inter-sector work environments. It is hoped that in the future it will be implemented as the fourth clinical modality in conjunction with the three already established clinical imaging techniques of magnetic resonance imaging (MRI), x-ray computed tomography (CT) and positron emission tomography (PET). The proposed project seeks to demonstrate that ZW800-1 (a novel zwitterionic Near Infra-Red Fluorescence (NIRF) dye), when conjugated onto a cRGD peptide, can be used to identify a minimum tumour margin distance during intra-operative image-guided surgery. These will be optimized to be used with clinical hand-held camera systems ArtemisTM, mini-FLARETM and MSOTTM . The overall aim is to aid the surgeon to visibly demarcate tumour from healthy tissue so that a complete image-guided surgical solution to cancer can be of benefit to patients and the healthcare system. Campo scientifico medical and health sciencesclinical medicinesurgeryengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsoptical sensorsnatural sciencesbiological sciencesbiochemistrybiomoleculesmedical and health sciencesclinical medicineoncologyengineering and technologymedical engineeringdiagnostic imagingmagnetic resonance imaging Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2013-IEF - Marie-Curie Action: "Intra-European fellowships for career development" Invito a presentare proposte FP7-PEOPLE-2013-IEF Vedi altri progetti per questo bando Meccanismo di finanziamento MC-IEF - Intra-European Fellowships (IEF) Coordinatore ACADEMISCH ZIEKENHUIS LEIDEN Contributo UE € 243 847,80 Indirizzo ALBINUSDREEF 2 2333 ZA Leiden Paesi Bassi Mostra sulla mappa Regione West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Jacobus De Graaf (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
