Circadian timing of metabolism in C. elegans

Projektinformationen

TIMETAB

ID Finanzhilfevereinbarung: 627263

Abgeschlossenes Projekt

Startdatum 1 Juli 2014

Enddatum 30 Juni 2016

Finanziert unter

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 223 002,20

EU-Beitrag € 223 002,20

Koordiniert durch

UNIVERSIDAD PABLO DE OLAVIDE
Spain

Ziel

We will investigate the role of the circadian clock in energy balance, metabolism and lifespan of C. elegans.
The evolution of life on Earth has been dominated by the influence of the daily rhythms imposed by its rotational movement. As a consequence, endogenous circadian clocks are present in organisms from all phyla, helping them to anticipate the daily cycles in their environment. This endogenous clock gets information from external cues (zeitgebers) in order to synchronise internal timing to the 24 h day. Circadian clocks regulate processes from gene expression to behaviour, resulting in rhythms in metabolite levels and food intake. The disruption of circadian rhythms has been linked to many pathological conditions, including sleep disorders, depression, metabolic syndrome and cancer. As obesity becomes epidemic in industrialized societies in parallel with a well-documented disruption of our circadian rhythms, the relationship between them becomes highly relevant. We propose to investigate this problem using the nematode C. elegans, an emergent model for the study of circadian rhythms and already established for metabolic research.

Wissenschaftliches Gebiet

• medical and health sciences › clinical medicine › psychiatry › sleep disorders
• medical and health sciences › clinical medicine › oncology
• medical and health sciences › health sciences › nutrition › obesity

Programm/Programme

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• FP7-PEOPLE-2013-IEF - Marie-Curie Action: "Intra-European fellowships for career development"

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2013-IEF
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IEF - Intra-European Fellowships (IEF)

Koordinator

UNIVERSIDAD PABLO DE OLAVIDE

Kontakt Verwaltung

Marta Mercado (Ms.)

• EU-Beitrag: € 223 002,20
• Adresse: CARRETERA DE UTRERA KM 1 ; 41013 Sevilla ; Spanien
• Region: Sur › Andalucía › Sevilla
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten