Molecularly Imprinted Nanofibres for Tissue Engineering, Affinity Depletion and Biosensor Applications

Projektinformationen

MIFS4BIOMED

ID Finanzhilfevereinbarung: 629251

Abgeschlossenes Projekt

Startdatum 1 September 2014

Enddatum 31 August 2016

Finanziert unter

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 275 138,80

EU-Beitrag € 275 138,80

Koordiniert durch

Linköping University
Sweden

Ziel

Molecular imprinted polymers and electrospun nanofibres are both hot topics individually in the biomedical sciences, with applications including tissue engineering, regenerative medicine, drug release, affinity chromatography and biosensors. This proposal combines these two leading-edge approaches to generate entirely novel materials with broad utility in biomedical engineering. Molecular imprinting is a form of template assisted synthesis that facilitates the creation of artificial receptors that can have affinity constants as high as their natural counterparts. Electrospinning (ES) is one of the most broadly used techniques for fabrication of nanostructured materials. ES uses electrical forces to produce continuous fibres having diameters in range of few nanometers to several micrometers. ES offers several technical advantages such as extremely high surface area per unit volume, tunable porosity, flexibility for adapting it to different shapes and sizes, and possibilities for controlling nanofibre composition.

In this proposal, we have focused on next generation molecular imprinting using reactive electrospinning to obtain directly imprinted nanofibres. We will demonstrate the utility of this new nanofabrication technology in three key areas: active agent carriers in regenerative medicine, affinity depleting membranes in blood-related proteomics, and biorecognition elements for biosensors. The multidisciplinary nature of the project will make important contributions to the development and validation of new therapies, sustainable and efficient healthcare systems, and strengthening the competitiveness and innovative capacity of European health-related industries. We will be working at the frontiers of two leading research areas having the potential to attract the attention of the researcher community not only in Europe, but also world wide, and to make significant contribution to EU’s research priorities, sustainable development and scientific competencies.

Wissenschaftliches Gebiet

• engineering and technology › electrical engineering, electronic engineering, information engineering › electronic engineering › sensors › biosensors
• natural sciences › biological sciences › biochemistry › biomolecules › proteins › proteomics
• medical and health sciences › medical biotechnology › tissue engineering
• natural sciences › chemical sciences › polymer sciences
• engineering and technology › nanotechnology › nano-materials

Programm/Programme

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• FP7-PEOPLE-2013-IEF - Marie-Curie Action: "Intra-European fellowships for career development"

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2013-IEF
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IEF - Intra-European Fellowships (IEF)

Koordinator

Linköping University

Kontakt Verwaltung

Pia Heidenberg (Mrs.)

• EU-Beitrag: € 275 138,80
• Adresse: CAMPUS VALLA ; 581 83 Linköping ; Schweden
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten