Objetivo There exists an urgent need to advance methods for detection of bacteria in the body, primarily in the context of infectious disease research. Real-time in vivo analysis empowers the investigator with the ability to non-invasively assess bacterial activity over time, as well as host responses to infection and interventions. Optical Imaging (OI) modalities are based on the detection and quantification of bioluminescent or fluorescent light from the subject and represent powerful yet cost-efficient and convenient systems. By labelling of bacteria and/or host cells of interest, both bacterial and host responses can be assessed in rapid, high-throughput analyses, providing spatial, temporal and quantitative read-out, without the need for radioactivity. There is a large and increasing market need for efficient reagents for in vivo bacterial imaging.We aim to develop improved in vivo imaging and ex vivo analysis methods for the study of bacterial infectious diseases and host immune response to infections, to address the current need across the range of fields of infectious disease and vaccine research. A broad skill set is required in this rapidly advancing field, involving exposure to laboratory science, imaging technology, commercialisation of research and industrial processes. By bringing together an international network of leaders in the fields of molecular imaging, infectious disease, vaccine research and industry, we propose to address the current paucity of technology for imaging of bacteria in research animals. Novartis is a world leader in development of vaccines for infectious diseases, and will provide an industrial steer from the project outset. Through combining the various specialities of this IAPP, the proposed work programme will facilitate transfer of knowledge among project partners, promote the development and training of staff in both academia and industry, as well as providing the industry partner with new R&D tools. Ámbito científico natural sciencesbiological sciencesmicrobiologybacteriologymedical and health scienceshealth sciencesinfectious diseasesmedical and health sciencesbasic medicineimmunologymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines Programa(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) FP7-PEOPLE-2013-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Convocatoria de propuestas FP7-PEOPLE-2013-IAPP Consulte otros proyectos de esta convocatoria Régimen de financiación MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Coordinador UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK Aportación de la UE € 623 601,28 Dirección WESTERN ROAD T12 YN60 Cork Irlanda Ver en el mapa Región Ireland Southern South-East Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo David O'connell (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Participantes (2) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE Suiza Aportación de la UE € 220 186,64 Dirección BATIMENT CE 3316 STATION 1 1015 Lausanne Ver en el mapa Región Schweiz/Suisse/Svizzera Région lémanique Vaud Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Elena Dubikovskaya (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos GLAXOSMITHKLINE VACCINES SRL Italia Aportación de la UE € 444 112,15 Dirección VIA FIORENTINA 1 53100 SIENA Ver en el mapa Región Centro (IT) Toscana Siena Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Francesco Siciliano (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos