CORDIS
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Strengthening Animal Production and Health through the Immune Response

Project information

Grant agreement ID: 633184

  • Start date

    1 March 2015

  • End date

    28 February 2019

Funded under:

H2020-EU.3.2.

  • Overall budget:

    € 10 549 121,50

  • EU contribution

    € 8 999 996,25

Coordinated by:

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT

France

Objective

SAPHIR aims to develop vaccine strategies effective against endemic pathogens responsible for high economic losses in livestock in order to strengthen the profitability of food animal systems, improve animal welfare and reduce xenobiotic usage in farming with a One Health perspective.

SAPHIR will bring novel vaccine strategies to the market i) at short term, with several promising vaccines brought to demonstration (RTL6), ii) at long term, with cutting edge strategies brought at proof of concept (RTL3) and iii) in line with socio-economic requirements. SAPHIR has selected two representative pathogens of pigs (Porcine Reproductive and Respiratory Syndrome Virus and Mycoplasma hyopneumoniae), chickens (Eimeria and Clostridium perfringens) and cattle (Bovine Respiratory Syncytial Virus, Mycoplasma bovis) to develop generic vaccine approaches applicable to other pathogens.

SAPHIR will issue i) knowledge of immune mechanisms of protection, ii) affordable, safe and multivalent vaccines with DIVA properties, iii) efficient adjuvants targeting dendritic cells, optimal formulations, new mucosal and skin delivery systems, a new generation of DNA vectors and viral replicon platforms for fostering an earlier and longer duration of immunity including the perinatal period, and iv) basal biomarkers of individual immuno-competence for future breeding strategies. The SAPHIR dissemination and training programme includes creation of an integrated health management website, launch of a Global Alliance for Veterinary Vaccines and organization of workshops directed at food animal system stakeholders. This will ensure optimal research translation of SAPHIR outputs to market and field applications.
SAPHIR brings together interdisciplinary expertise from fourteen academic institutes including a Chinese partner, five SMEs and two pharmaceutical companies.

Coordinator

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT

Address

Rue De L'Universite 147
75338 Paris Cedex 07

France

Activity type

Research Organisations

EU Contribution

€ 2 191 579,38

Participants (21)

CARDIFF UNIVERSITY

United Kingdom

EU Contribution

€ 319 743,75

EIDGENOESSISCHES DEPARTEMENT DES INNERN

Switzerland

EU Contribution

€ 1 200

EUROPEAN FORUM OF FARM ANIMAL BREEDERS

Netherlands

EU Contribution

€ 150 893,75

INMUNOLOGIA Y GENETICA APLICADA SA

Spain

EU Contribution

€ 445 193,75

INRA TRANSFERT SAS

France

EU Contribution

€ 365 176,25

PARCO TECNOLOGICO PADANO S.R.L.

Italy

EU Contribution

€ 278 868,75

Shanghai Veterinary Research Institute - Chinese Academy of Agricultural Sciences

China

SPOREGEN LIMITED

United Kingdom

EU Contribution

€ 224 993,75

STICHTING WAGENINGEN RESEARCH

Netherlands

EU Contribution

€ 772 092,50

SVERIGES LANTBRUKSUNIVERSITET

Sweden

EU Contribution

€ 323 788,75

SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO

Poland

EU Contribution

€ 92 731,25

THE PIRBRIGHT INSTITUTE LBG

United Kingdom

EU Contribution

€ 289 067,50

THE ROYAL VETERINARY COLLEGE

United Kingdom

EU Contribution

€ 458 846,25

UNIVERSITAET BERN

Switzerland

EU Contribution

€ 31 437,50

UNIVERSITE DE LAUSANNE

Switzerland

UNIVERSITEIT GENT

Belgium

EU Contribution

€ 1 234 978,50

THE UNIVERSITY OF EDINBURGH

United Kingdom

EU Contribution

€ 802 187,19

VACCIBODY AS

Norway

EU Contribution

€ 334 368,75

VIRBAC SA

France

XEOLAS PHARMACEUTICALS LIMITED

Ireland

EU Contribution

€ 391 993,68

THE UNIVERSITY OF LIVERPOOL

United Kingdom

EU Contribution

€ 290 855

Project information

Grant agreement ID: 633184

  • Start date

    1 March 2015

  • End date

    28 February 2019

Funded under:

H2020-EU.3.2.

  • Overall budget:

    € 10 549 121,50

  • EU contribution

    € 8 999 996,25

Coordinated by:

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT

France

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