Objective
"The dramatic differentials in healthy ageing, quality of life and life expectancy between individuals of different socioeconomic groups, is a major societal challenge facing Europe. The overarching aim of the LIFEPATH project is to understand the determinants of diverging ageing pathways among individuals belonging to different socio-economic groups. This will be achieved via an original study design that integrates social science approaches with biology (including molecular epidemiology), using existing population cohorts and omics measurements (particularly epigenomics). The specific objectives of the project are: (a) To show that healthy ageing is an achievable goal for society, as it is already experienced by individuals of high socio-economic status (SES); (b) To improve the understanding of the mechanisms through which healthy ageing pathways diverge by SES, by investigating lifecourse biological pathways using omic technologies; (c) To examine the consequences of the current economic recession on health and the biology of ageing (and the consequent increase in social inequalities); (d) To provide updated, relevant and innovative evidence for healthy ageing policies (particularly “health in all policies”) that address social disparities in ageing and the social determinants of health, using both observational studies as well as an experimental approach based on the existing ""conditional cash transfer"" experiment in New York.
To achieve these objectives we will use data from three categories of studies: 1. Europe-wide or national surveys combined with population registry data; 2. Cohorts with intense phenotyping and repeat biological samples (total population >33,000); 3. Large cohorts with biological samples (total population >202,000). The cohorts will provide information on healthy ageing at different stages of life, based on the concepts of life-course epidemiology (""build-up and decline"") and multimorbidity.
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Fields of science
- humanitieshistory and archaeologyhistorymedieval history
- medical and health scienceshealth sciencespublic healthepidemiology
- medical and health sciencesclinical medicineendocrinologydiabetes
- social sciencessociologysocial issuessocial inequalities
- medical and health scienceshealth sciencesnutritionobesity
Programme(s)
Topic(s)
Funding Scheme
RIA - Research and Innovation action
Coordinator
SW7 2AZ London
United Kingdom
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Participants (16)
WC1E 6BT London
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1011 Lausanne
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31062 Toulouse Cedex 9
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3015 GD Rotterdam
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Participation ended
WC2A 2AE London
10027 7003 New York
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Participation ended
00250 Helsinki
10138 Torino
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75654 Paris
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4050 290 Porto
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
3004 Melbourne Victoria
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D02 CX56 Dublin 2
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10124 Torino
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20131 Milano
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
WC2R 2LS London
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00014 Helsingin Yliopisto
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