CORDIS
Resultados de investigaciones de la UE

CORDIS

Español ES

Advanced nanophotonic point-of-care analysis device for fast and early diagnosis of cardiovascular diseases

Información del proyecto

Identificador del acuerdo de subvención: 634013

Estado

Proyecto cerrado

  • Fecha de inicio

    1 Septiembre 2015

  • Fecha de finalización

    28 Febrero 2019

Financiado con arreglo a:

H2020-EU.3.1.3.

  • Presupuesto general:

    € 4 146 163,75

  • Aportación de la UE

    € 3 593 962

Coordinado por:

UNIVERSITAT POLITECNICA DE VALENCIA

España

Objetivo

The PHOCNOSIS project aims at the development and the preclinical validation of a nanotechnology-based handheld point-of-care testing (POCT) analysis device for its application in the early diagnosis of cardiovascular diseases (CVD). The diagnosis will be carried out by means of the fast (<10 minutes), ultra-sensitive (<1 ng/L) and label-free detection of multiple cardiac biomarkers, using a small volume of whole blood (<100 μL). This POCT analysis device will significantly help in the implementation of mass screening programs, with the consequent impact on clinical management, reducing also costs of treatments, and increasing survival rates.
The PHOCNOSIS analysis device will be based on two state-of-the-art technological elements in order to obtain a compact and highly sensitive final device. First, an integrated micro-/nanofluidic system will be used for biomarkers separation, purification and concentration, targeting an effective concentration increase by a factor greater than 1000x for the targeted biomarkers. Then, the concentrated biomarkers will be detected using a novel nanophotonic-based sensing technique, envisaging a final combined detection limit below 1 ng/L. This novel sensing technique allows us to obtain systems which are low-cost, compact and with a lower complexity, thus making them suitable for the development of portable devices for POCT. The PHOCNOSIS project will target the deployment of disposable biochips with an envisaged cost below €3 to be used in a handheld analysis device with an envisaged cost below €3000.
Special attention will be paid within the PHOCNOSIS project to explore the potential deployment and commercialisation of the analysis device, by means of the involvement of relevant academic and industrial partners, as well as end users.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinador

UNIVERSITAT POLITECNICA DE VALENCIA

Dirección

Camino De Vera Sn Edificio 3a
46022 Valencia

España

Tipo de actividad

Higher or Secondary Education Establishments

Aportación de la UE

€ 1 097 891

Participantes (10)

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Alemania

Aportación de la UE

€ 409 050

UNIVERSITEIT TWENTE

Países Bajos

Aportación de la UE

€ 423 731

AALBORG UNIVERSITET

Dinamarca

Aportación de la UE

€ 344 915

CDA GMBH

Alemania

Aportación de la UE

€ 336 537,50

EV GROUP E. THALLNER GMBH

Austria

Aportación de la UE

€ 257 650

BIONOS BIOTECH SL

España

Aportación de la UE

€ 227 000

ART OF TECHNOLOGY AG

Suiza

ST GEORGE'S HOSPITAL MEDICAL SCHOOL

Reino Unido

Aportación de la UE

€ 315 937,50

GENERA BIOTECH SL

España

Aportación de la UE

€ 49 734,44

DB VENTURE BUILDER SL

España

Aportación de la UE

€ 131 515,56

Información del proyecto

Identificador del acuerdo de subvención: 634013

Estado

Proyecto cerrado

  • Fecha de inicio

    1 Septiembre 2015

  • Fecha de finalización

    28 Febrero 2019

Financiado con arreglo a:

H2020-EU.3.1.3.

  • Presupuesto general:

    € 4 146 163,75

  • Aportación de la UE

    € 3 593 962

Coordinado por:

UNIVERSITAT POLITECNICA DE VALENCIA

España