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  • Exploring the combined role of genetic and non-genetic factors for developing Age-Related Macular Degeneration: A systems level analysis of disease subgroups, risk factors, and pathways
H2020

EYE-RISK

Project ID: 634479
Financiado con arreglo a

Exploring the combined role of genetic and non-genetic factors for developing Age-Related Macular Degeneration: A systems level analysis of disease subgroups, risk factors, and pathways

Desde 2015-05-01 hasta 2019-04-30, proyecto en curso

Detalles del proyecto

Coste total:

EUR 6 069 996,25

Aportación de la UE:

EUR 5 972 496

Coordinado en:

Germany

Convocatoria de propuestas:

H2020-PHC-2014-two-stageSee other projects for this call

Régimen de financiación:

RIA - Research and Innovation action

Objetivo

Deliverables

  • EYE-RISK website

    Establishment and launch of the EYE-RISK website; creation of a website with two levels of accessibility, one for the public and one restricted to project members; regular updates after launch of the website.

  • Dissemination

    EYE-RISK leaflets or leporellos developed, designed and sent to beneficiaries for further distribution/dissemination.

Publications

  • Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model
    Author(s): Matthew G. Pilgrim, Imre Lengyel, Antonio Lanzirotti, Matt Newville, Sarah Fearn, Eszter Emri, Jonathan C. Knowles, Jeffrey D. Messinger, Russell W. Read, Clyde Guidry, Christine A. Curcio
    Published in: Investigative Opthalmology & Visual Science, issue 58/2, 2017. Page(s) 708.  ISSN: 1552-5783
    DOI: 10.1167/iovs.16-21060
  • Simple and complex retinal dystrophies are associated with profoundly different disease networks
    Author(s): Christina Kiel, Claire Lastrucci, Philip J. Luthert, Luis Serrano
    Published in: Scientific Reports, issue 7, 2017. Page(s) 41835.  ISSN: 2045-2322
    DOI: 10.1038/srep41835
  • Prevalence of Age-Related Macular Degeneration in Europe
    Author(s): Johanna M. Colijn, Gabriëlle H.S. Buitendijk, Elena Prokofyeva, Dalila Alves, Maria L. Cachulo, Anthony P. Khawaja, Audrey Cougnard-Gregoire, Bénédicte M.J. Merle, Christina Korb, Maja G. Erke, Alain Bron, Eleftherios Anastasopoulos, Magda A. Meester-Smoor, Tatiana Segato, Stefano Piermarocchi, Paulus T.V.M. de Jong, Johannes R. Vingerling, Fotis Topouzis, Catherine Creuzot-Garcher, Geir Bertelsen, Norbert Pfeiffer, Astrid E. Fletcher, Paul J. Foster, Rufino Silva, Jean-François Korobelnik, Cécile Delcourt, Caroline C.W. Klaver, Soufiane Ajana, Blanca Arango-Gonzalez, Verena Arndt, Vaibhav Bhatia, Shomi S. Bhattacharya, Marc Biarnés, Anna Borrell, Sebastian Bühren, Sofia M. Calado, Johanna M. Colijn, Audrey Cougnard-Grégoire, Sascha Dammeier, Eiko K. de Jong, Berta De la Cerda, Cécile Delcourt, Anneke I. den Hollander, Francisco J. Diaz-Corrales, Sigrid Diether, Eszter Emri, Tanja Endermann, Lucia L. Ferraro, Míriam Garcia, Thomas J. Heesterbeek, Sabina Honisch, Carel B. Hoyng, Eveline Kersten, Ellen Kilger, Caroline C.W. Klaver, Hanno Langen, Imre Lengyel, Phil Luthert, Cyrille Maugeais, Magda Meester-Smoor, Bénédicte M.J. Merle, Jordi Monés, Everson Nogoceke, Tunde Peto, Frances M. Pool, Eduardo Rodríguez, Marius Ueffing, Karl U. Ulrich Bartz-Schmidt, Elisabeth M. van Leeuwen, Timo Verzijden, Markus Zumbansen, Niyazi Acar, Eleftherios Anastosopoulos, Augusto Azuara-Blanco, Arthur Bergen, Geir Bertelsen, Christine Binquet, Alan Bird, Lionel Brétillon, Alain Bron, Gabrielle Buitendijk, Maria Luz Cachulo, Usha Chakravarthy, Michelle Chan, Petrus Chang, Johanna Colijn, Audrey Cougnard-Grégoire, Catherine Creuzot-Garcher, Philippa Cumberland, José Cunha-Vaz, Vincent Daien, Gabor Deak, Cécile Delcourt, Marie-Noëlle Delyfer, Anneke den Hollander, Martha Dietzel, Maja Gran Erke, Sascha Fauser, Robert Finger, Astrid Fletcher, Paul Foster, Panayiota Founti, Arno Göbel, Theo Gorgels, Jakob Grauslund, Franz Grus, Christopher Hammond, Catherine Helmer, Hans-Werner Hense, Manuel Hermann, René Hoehn, Ruth Hogg, Frank Holz, Carel Hoyng, Nomdo Jansonius, Sarah Janssen, Anthony Khawaja, Caroline Klaver, Jean-François Korobelnik, Julia Lamparter, Mélanie Le Goff, Sergio Leal, Yara Lechanteur, Terho Lehtimäki, Andrew Lotery, Irene Leung, Matthias Mauschitz, Bénédicte Merle, Verena Meyer zu Westrup, Edoardo Midena, Stefania Miotto, Alireza Mirshahi, Sadek Mohan-Saïd, Michael Mueller, Alyson Muldrew, Sandrina Nunes, Konrad Oexle, Tunde Peto, Stefano Piermarocchi, Elena Prokofyeva, Jugnoo Rahi, Olli Raitakari, Luisa Ribeiro, Marie-Bénédicte Rougier, José Sahel, Aggeliki Salonikiou, Clarisa Sanchez, Steffen Schmitz-Valckenberg, Cédric Schweitzer, Tatiana Segato, Jasmin Shehata, Rufino Silva, Giuliana Silvestri, Christian Simader, Eric Souied, Henriet Springelkamp, Robyn Tapp, Fotis Topouzis, Virginie Verhoeven, Therese Von Hanno, Stela Vujosevic, Katie Williams, Christian Wolfram, Jennifer Yip, Jennyfer Zerbib, Isabella Zwiener
    Published in: Ophthalmology, 2017.  ISSN: 0161-6420
    DOI: 10.1016/j.ophtha.2017.05.035
  • The unconventional secretion of ARMS2
    Author(s): Elod Kortvely, Stefanie M. Hauck, Jennifer Behler, Nurulain Ho, Marius Ueffing
    Published in: Human Molecular Genetics, 2016. Page(s) ddw162.  ISSN: 0964-6906
    DOI: 10.1093/hmg/ddw162
  • Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration
    Author(s): Eveline Kersten, Constantin C. Paun, Rosa L. Schellevis, Carel. B. Hoyng, Cécile Delcourt, Imre Lengyel, Tunde Peto, Marius Ueffing, Caroline C.W. Klaver, Sascha Dammeier, Anneke I. den Hollander, Eiko K. de Jong
    Published in: Survey of Ophthalmology, 2017.  ISSN: 0039-6257
    DOI: 10.1016/j.survophthal.2017.05.003
  • Drusen Ooze: A Novel Hypothesis in Geographic Atrophy
    Author(s): Jordi Monés, Míriam Garcia, Marc Biarnés, Aparna Lakkaraju, Lucia Ferraro
    Published in: Ophthalmology Retina, 2017.  ISSN: 2468-6530
    DOI: 10.1016/j.oret.2017.02.006
  • Geographic atrophy phenotype identification by cluster analysis
    Author(s): Jordi Monés, Marc Biarnés
    Published in: British Journal of Ophthalmology, 2017. Page(s) bjophthalmol-2017-310268.  ISSN: 0007-1161
    DOI: 10.1136/bjophthalmol-2017-310268

Coordinador

EBERHARD KARLS UNIVERSITAET TUEBINGEN
Germany

Aportación de la UE: EUR 1 360 875


GESCHWISTER-SCHOLL-PLATZ
72074 TUEBINGEN
Germany
Activity type: Higher or Secondary Education Establishments

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Participantes

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

Aportación de la UE: EUR 962 250


S GRAVENDIJKWAL 230
3015 CE ROTTERDAM
Netherlands
Activity type: Higher or Secondary Education Establishments

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FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain

Aportación de la UE: EUR 360 000


CARRER DOCTOR AIGUADER 88
08003 BARCELONA
Spain
Activity type: Research Organisations

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STICHTING KATHOLIEKE UNIVERSITEIT
Netherlands

Aportación de la UE: EUR 539 375


GEERT GROOTEPLEIN NOORD 9
6525 EZ NIJMEGEN
Netherlands
Activity type: Higher or Secondary Education Establishments

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UNIVERSITE DE BORDEAUX
France

Aportación de la UE: EUR 416 875


PLACE PEY BERLAND 35
33000 BORDEAUX
France
Activity type: Higher or Secondary Education Establishments

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UNIVERSITY COLLEGE LONDON
United Kingdom

Aportación de la UE: EUR 501 992,11


GOWER STREET
WC1E 6BT LONDON
United Kingdom
Activity type: Higher or Secondary Education Establishments

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FUNDACION BARCELONA MACULA FOUNDATION RESEARCH FOR VISION
Spain

Aportación de la UE: EUR 320 531


CARRER HORACI 41/43 Esc B
08022 BARCELONA
Spain
Activity type: Research Organisations

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PRO RETINA DEUTSCHLAND
Germany

Aportación de la UE: EUR 106 250


VAALSER STRASSE 108
52074 AACHEN
Germany
Activity type: Other

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AYOXXA BIOSYSTEMS GMBH
Germany

Aportación de la UE: EUR 608 500


Nattermannallee 1
50829 Cologne
Germany
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)

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F. HOFFMANN-LA ROCHE AG
Switzerland

Aportación de la UE: EUR 0


GRENZACHERSTRASSE 124
4070 BASEL
Switzerland
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)

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MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST
La participación finalizó
United Kingdom

Aportación de la UE: EUR 124,38


City Road 162
EC1V 2PD LONDON
United Kingdom
Activity type: Research Organisations

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FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD
Spain

Aportación de la UE: EUR 198 607,50


AVENIDA AMERICO VESPUCIO 15 EDIF S2
41092 SEVILLA
Spain
Activity type: Research Organisations

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THE QUEEN'S UNIVERSITY OF BELFAST
United Kingdom

Aportación de la UE: EUR 592 116,01


UNIVERSITY ROAD LANYON BUILDING
BT7 1NN BELFAST
United Kingdom
Activity type: Higher or Secondary Education Establishments

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UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland

Aportación de la UE: EUR 5 000


BELFIELD
4 DUBLIN
Ireland
Activity type: Higher or Secondary Education Establishments

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