CORDIS
EU research results

CORDIS

English EN

Tools And Strategies to access to original bioactive compounds from Cultivation of MARine invertebrates and associated symbionts

Objective

TASCMAR project aspires to develop new tools and strategies in order to overcome existing bottlenecks in the biodiscovery and industrial exploitation of novel marine derived biomolecules (secondary metabolites and enzymes) with applications in the pharmaceuticals, nutraceuticals, cosmeceuticals and fine chemicals industries. Exploitation of neglected and underutilized marine invertebrates and symbionts from mesophotic zone will be combined with innovative approaches for the cultivation and extraction of marine organisms from lab to pilot-scale, using the unique prototypes Platotex™ and Zippertex™, both reaching the Technology Readiness Level 7. Thus, marine dedicated cultivation and extraction equipment will be built and validated. These unique improvements will ensure sustainable supply of biomass and promote the production of high added value bioactive marine compounds. An integrated, holistic technological metabolomic approach will be applied, in conjunction with bioactivity profiling, as filtering and bio-prioritisation tools. Moreover, state-of-the-art analytical instrumentation and in-house databases will be employed for the dereplication and characterization of valuable compounds. A panel of libraries (marine organisms, extracts, pure metabolites and biocatalysts) will be constructed and exploited throughout the project. A focused panel of in-vitro, cell-based, in-ovo and in-vivo bioassays for discovering metabolites with anti-ageing and/or angiogenesis modulating activity will frame the entire work-flow and will reveal the lead compounds. In addition, the catalytic potential of mesophotic symbionts and deriving enzymes candidates will be evaluated in fine chemicals and bioremediation industries. The project activities will be constantly assessed via effective management for their societal, economical and environmental impact in order to find the best compromise between industrial development and sustainable growth.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

Address

Rue Michel Ange 3
75794 Paris

France

Activity type

Research Organisations

EU Contribution

€ 1 442 248,75

Participants (12)

Sort alphabetically

Sort by EU Contribution

Expand all

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON

Greece

EU Contribution

€ 801 250

TEL AVIV UNIVERSITY

Israel

EU Contribution

€ 400 278

CHULALONGKORN UNIVERSITY

Thailand

EU Contribution

€ 299 975

UNIVERSITE DE LA REUNION

France

EU Contribution

€ 399 917,50

CRELUX GMBH

Germany

EU Contribution

€ 801 212,50

BICT SRL

Italy

EU Contribution

€ 320 875

PIERRE GUERIN SAS

France

EU Contribution

€ 800 015

IMARE NATURAL SL

Spain

EU Contribution

€ 299 956

ASTAREAL AB

Sweden

EU Contribution

€ 232 900

APIVITA KALLYNTIKA DIAITITIKA FARMAKA ANONYMI EMPORIKI KAI VIOTECHNIKI ETAIREIA

Greece

EU Contribution

€ 399 687,50

T6 ECOSYSTEMS SRL

Italy

EU Contribution

€ 208 000

ASSOCIATION ECO OCEAN

Israel

EU Contribution

€ 349 635

Project information

Grant agreement ID: 634674

Status

Closed project

  • Start date

    1 April 2015

  • End date

    31 March 2019

Funded under:

H2020-EU.3.2.

  • Overall budget:

    € 6 758 452,50

  • EU contribution

    € 6 755 950,25

Coordinated by:

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

France