Objective
Differential cancer diagnosis takes place daily in clinical settings for a better monitoring of patient responses to existing treatments. However outcome of this diagnosis is today still poor. Moreover, current technology to measure biomarker levels is expensive and sophisticated.
Most cancer biomarker analysis use blood or biological tissues as the main source of material. These biopsies must be analyzed in specialized laboratories incurring in some limitations: high cost; specialized personnel and equipment; large amounts of biological material; long outcome delivery time; time consuming processes.
Therefore it exist a real need and urgency to have new diagnostic devices that provide diagnosis, prognosis, and monitoring data faster and with exquisite ultra-sensitivity on time to take the appropriate decisions to improve personalized diagnosis and therapy.
The aim of GLAM project is to provide an innovative device to fulfill these requirements using soluble biomarkers for personalized diagnosis and therapy monitoring.
Specifically we will design and develop a new diagnostic tool to detect biomarkers from biofluids obtained in a non-invasive manner, specifically focusing to urine and to genitourinary cancers, to help oncologist to take better treatment decisions, approaching personalized medicine.
GLAM will develop an integrated device based on novel label-free photonic biosensors with ultra-sensitivity, simplicity of use, portability, multiplexing and low cost. GLAM capitalizes on the unprecedented sensitivity achieved using laser microring resonators to detect key biomarkers in tumor development and treatment. Point of Care of the device will be carried out by preclinical and clinical sample analysis of genitourinary cancer patients to warrant personalized medicine.
Importantly the GLAM unique technology will make the device also usable with other biofluids and might also be used to help physicians with other biomarker driven.
Fields of science
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensors
- medical and health sciencesclinical medicineoncologybladder cancer
- medical and health scienceshealth sciencespersonalized medicine
- engineering and technologymedical engineeringmedical laboratory technologydiagnostic technologies
- natural sciencesphysical sciencesopticslaser physics
Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
08225 Terrassa
Spain
See on map
Participants (9)
08028 Barcelona
See on map
7522 NB Enschede
See on map
67017 Tel Aviv-jaffo
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1050 Bruxelles
See on map
08860 Castelldefels
See on map
6525 XZ Nijmegen
See on map
11000 Beograd
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
EH54 7DQ Livingston
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1030 Bruxelles
See on map
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.