CORDIS
Forschungsergebnisse der EU

CORDIS

Deutsch DE
Sustainable industrial processes based on a C-C bond-forming enzyme platform

Sustainable industrial processes based on a C-C bond-forming enzyme platform

Ziel

C-C bond forming reactions are at the heart of industrial organic synthesis, but remain largely unexplored due to long development timelines and the lack of broad biocatalytic reaction platforms. CARBAZYMES addresses these challenges by assembling an interdisciplinary and intersectoral consortium as a powerful synergistic tool to promote innovation in the field of biocatalytic C-C bond formation at large scale, and thus the global competitiveness of the European chemical and pharmaceutical industry. The proposed consortium, with 50% industrial participation, represents academia but also commercial interests in different stages of the research-to-market process. This top-down approach, together with a life-cycle innovation approach ensures an industrial drive to the project.
Clearly aligned with the scope of topic BIOTEC3-2014, CARBAZYMES will pursue the biocatalytic synthesis (spanning TRLs 5-7) of 4 APIs and 3 bulk chemicals –corresponding to market needs detected by the industrial partners in the Consortium. This will be accomplished through an inter-disciplinary approach which includes: i) a broad platform of 4 types of unique C-C bond-forming enzymes, mostly lyases; ii) the capacity to rapidly evolve enzymes to operate under industrial conditions by means of novel enzyme panels and massive screening methods; iii) application of microreactor technology for bioprocess characterization; iv) demonstration actions comprising technical (up to 100L) and economic viability studies carried out by industrial partners.
CARBAZYMES unmistakably aims to have social and economic impact by addressing markets worth bn €, developing enzyme evolution technologies beyond the state of the art and creating qualified jobs and technical-scale facilities at the industrial partners’ sites. CARBAZYMES will also achieve an environmental impact by enforcing that the developed processes replace more energy and resource intensive processes, thus leading to reduced environmental footprints.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Koordinator

TECHNISCHE UNIVERSITAT DARMSTADT

Adresse

Karolinenplatz 5
64289 Darmstadt

Deutschland

Aktivitätstyp

Higher or Secondary Education Establishments

EU-Beitrag

€ 1 469 606

Beteiligte (14)

Alphabetisch sortieren

Nach EU-Beitrag sortieren

Alles aufklappen

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Spanien

EU-Beitrag

€ 1 145 190

UNIVERSIDAD AUTONOMA DE MADRID

Spanien

EU-Beitrag

€ 786 375

TECHNISCHE UNIVERSITAET BRAUNSCHWEIG

Deutschland

EU-Beitrag

€ 677 018

RIJKSUNIVERSITEIT GRONINGEN

Niederlande

EU-Beitrag

€ 726 452

SVEUCILISTE U ZAGREBU FAKULTET KEMIJSKOG INZENJERSTVA I TEHNOLOGIJE

Kroatien

EU-Beitrag

€ 544 260

BIOCHEMIZE SL

Spanien

EU-Beitrag

€ 207 987

BIO-PRODICT BV

Niederlande

EU-Beitrag

€ 463 736

SUSTAINABLE MOMENTUM SL

Spanien

EU-Beitrag

€ 109 200

INSTITUT UNIV DE CIENCIA I TECNOLOGIA SA

Spanien

EU-Beitrag

€ 416 325

ENZYMICALS AG

Deutschland

EU-Beitrag

€ 380 800

ALBERT-LUDWIGS-UNIVERSITAET FREIBURG

Deutschland

EU-Beitrag

€ 412 500

PROZOMIX LIMITED

Vereinigtes Königreich

EU-Beitrag

€ 384 892

EVONIK INDUSTRIES AG

Deutschland

EVONIK CREAVIS GMBH

Deutschland

EU-Beitrag

€ 478 625

Projektinformationen

ID Finanzhilfevereinbarung: 635595

Status

Abgeschlossenes Projekt

  • Startdatum

    1 April 2015

  • Enddatum

    31 März 2019

Finanziert unter:

H2020-EU.2.1.4.

  • Gesamtbudget:

    € 9 251 355

  • EU-Beitrag

    € 8 202 966

Koordiniert durch:

TECHNISCHE UNIVERSITAT DARMSTADT

Deutschland