CORDIS
EU research results

CORDIS

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BreAking the Link betweeN myo10 and CancEr

Project information

Grant agreement ID: 641346

  • Start date

    1 May 2015

  • End date

    31 October 2016

Funded under:

H2020-EU.1.1.

  • Overall budget:

    € 150 000

  • EU contribution

    € 150 000

Hosted by:

TURUN YLIOPISTO

Finland

Objective

Breast cancer is the most frequently diagnosed cancer form and the leading cause of death among women while pancreatic cancer is the fourth commonest cause of cancer-related mortality across the world and very difficult to treat due to its aggressive nature and the relative lack of curative options. A major impediment in the identification of new therapeutic targets lies in our limited understanding of the exact mechanisms taking place within the tumor microenvironment that are responsible for the development of cancer, progression and metastasis. Based on our recent experiments, we have found that high expression of an actin-binding protein correlates with poor clinical prognosis in breast and pancreatic cancer patients. Drawing upon our recent findings, the target of the PoC project is two-fold. First, to (i) validate the clinical application of our novel therapeutic concept by conducting a series of in-vitro and in-vivo tests on a set of 22 Myo10 inhibitory lead-compounds (i.e. “hits”) which were identified via High-Throughput Screening (HTS). Second, to (ii) take the necessary steps towards the definition of the best business path in view of the strong pre-commercialization potential.

Host institution

TURUN YLIOPISTO

Address

Yliopistonmaki
20014 Turku

Finland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 150 000

Beneficiaries (1)

TURUN YLIOPISTO

Finland

EU Contribution

€ 150 000

Project information

Grant agreement ID: 641346

  • Start date

    1 May 2015

  • End date

    31 October 2016

Funded under:

H2020-EU.1.1.

  • Overall budget:

    € 150 000

  • EU contribution

    € 150 000

Hosted by:

TURUN YLIOPISTO

Finland