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RNA-based technologies for single-cell metabolite analysis

Objective

Metabolism is the foundation of all living organisms. While cells in a population are often phenotypically different, most of our current analytical approaches still probe metabolism only at the population level. Because strong evidence exists that metabolic cell-to-cell heterogeneity has, for instance, disease relevance, researcher from MetaRNA will overcome this severe analytical limitation through exploiting exciting opportunities emerging from the RNA field. Such synergy potential between the metabolism and RNA research fields has until today not been exploited, because they are separated from each other in Europe and worldwide. Through consequently missing research training programs we thus lack experts with combined knowledge in metabolism and RNA. The aim of the MetaRNA proposal is therefore to establish a European Training Network (ETN) that educates specialists for academia and industry - fully trained at the interface of these two fields - in the development and application of RNA-based sensors to investigate metabolism at the single-cell level, to apply these tools for novel biotechnological applications and to provide a framework for their future use in diagnostics and therapeutics. In MetaRNA, eight research groups from the metabolic and RNA fields and six partners from the private sector join forces to create a platform of mobility and training to 15 early-stage researchers (ESRs), by means of customized research projects, exchange of knowhow among researchers and partners, attendance to specialized courses, workshops and conferences, as well as training in complementary skills.

Call for proposal

H2020-MSCA-ITN-2014
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

RIJKSUNIVERSITEIT GRONINGEN
Address
Broerstraat 5
9712CP Groningen
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 510 748,56

Participants (10)

MEDICAL RESEARCH COUNCIL

Participation ended

United Kingdom
EU contribution
€ 22 773,99
Address
North Star Avenue Polaris House 2 Floor David Phillips Building
SN2 1FL Swindon
Activity type
Research Organisations
RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN
Germany
EU contribution
€ 498 432,96
Address
Regina Pacis Weg 3
53113 Bonn
Activity type
Higher or Secondary Education Establishments
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 580 163,76
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY OF WARWICK
United Kingdom
EU contribution
€ 273 287,88
Address
Kirby Corner Road - University House
CV4 8UW Coventry
Activity type
Higher or Secondary Education Establishments
TECHNISCHE UNIVERSITAT DARMSTADT
Germany
EU contribution
€ 498 432,96
Address
Karolinenplatz 5
64289 Darmstadt
Activity type
Higher or Secondary Education Establishments
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 525 751,20
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
KOBENHAVNS UNIVERSITET
Denmark
EU contribution
€ 290 081,88
Address
Norregade 10
1165 Kobenhavn
Activity type
Higher or Secondary Education Establishments
BIOSYNTIA APS
Denmark
EU contribution
€ 290 081,88
Address
Kogle Alle 6
2970 Horsholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DSM FOOD SPECIALTIES BV
Netherlands
EU contribution
€ 255 374,28
Address
Alexander Fleminglaan 1
2613 AX Delft
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE FRANCIS CRICK INSTITUTE LIMITED
United Kingdom
EU contribution
€ 250 513,89
Address
1 Midland Road
NW1 1AT London
Activity type
Research Organisations

Partners (4)

APTAIT GMBH
Germany
Address
Leonhardistrasse 2E
86911 Diessen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EVOLVA AG
Switzerland
Address
Duggingerstrasse 23
4153 Reinach
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ASSOCIATION POUR LE DEVELOPPEMENT DE L'ENSEIGNEMENT ET DES RECHERCHES AUPRES DES UNIVERSITES, DES CENTRES DE RECHERCHE ET DES ENTREPRISES D'AQUITAINE
France
Address
Avenue Du Docteur Albert Schweitzer - Centre Condorcet 162
33608 Pessac
Activity type
Research Organisations
TPP Global Development
United Kingdom
Address
Edinburgh Bioquarter
EH16 4UX Edinburgh
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)