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Research Training Network on Integrated Component Cycling in Epithelial Cell Motility

Research Training Network on Integrated Component Cycling in Epithelial Cell Motility

Objective

Cell migration (cell motility) is a fundamental biological process that is pivotal in (i) tissue formation and repair (health) and (ii) tissue invasion during carcinogenesis (disease). Understanding and controlling cell migration will have major clinical impact. Clarifying mechanisms driving cell motility has been challenging due to the complex underlying cellular mechanisms; these involve multiple components coordinated by structural, chemical and physical signals in terms of time and space. To accomplish breakthroughs in this field, researchers are needed who (i) master cutting-edge experimental techniques for monitoring the different cellular processes at high resolution and (ii) have competencies in theoretical science for integrating the resulting data sets into mechanistic mathematical models for predicting motile cell behaviour.
The Research Training Network on Integrated Component Cycling in Epithelial Cell Motility (InCeM) aims to endow up-and-coming researchers with exactly these competencies. They will be able to develop and apply innovative devices for microscopic recording, image processing techniques, data analysis tools and modelling procedures for mechanistic understanding of cell migration. InCeM will focus on epithelial cells, since inducing motility in this cell type is clinically relevant for wound healing and cancer invasion. The ultimate goal is to control and manipulate cell migration for clinical applications. A dedicated multidisciplinary team of 11 beneficiaries from universities (4), research institutions (4) and industry (3), based in 5 European countries and Israel, together with 17 associated partners from the public and private sector, will train 15 Early Stage Researchers (ESRs) to use the relevant technologies and sciences and will offer business training to prepare them for successful careers in both academic and non-academic environments.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

UNIVERSITAETSKLINIKUM AACHEN

Address

Pauwelsstrasse 30
52074 Aachen

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 498 432,96

Participants (11)

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FORSCHUNGSZENTRUM JULICH GMBH

Germany

EU Contribution

€ 498 432,96

WEIZMANN INSTITUTE OF SCIENCE

Israel

EU Contribution

€ 260 300,52

UNIVERSITAET DUISBURG-ESSEN

Germany

EU Contribution

€ 249 216,48

SOFTWARE COMPETENCE CENTER HAGENBERG GMBH

Austria

EU Contribution

€ 511 868,16

TEL AVIV UNIVERSITY

Israel

EU Contribution

€ 260 300,52

University of Sussex

United Kingdom

EU Contribution

€ 546 575,76

KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW

Netherlands

EU Contribution

€ 170 249,52

ANDOR TECHNOLOGY LIMITED

United Kingdom

EU Contribution

€ 273 287,88

IBIDI GMBH

Germany

EU Contribution

€ 249 216,48

GRADIENTECH AB

Sweden

EU Contribution

€ 263 659,32

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS

Netherlands

EU Contribution

€ 85 124,76

Partners (17)

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EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH

UPPSALA UNIVERSITET

Uppsala Innovation Centre

Johann Radon Institute for Computational and Applied Mathematics

SIRION BIOTECH GMBH

CARL ZEISS MICROSCOPY GMBH

LfB

UNIVERSITY OF MANITOBA

NETHERLANDS TRANSLATIONAL RESEARCH CENTER BV

Center for Entrepeneurship

TTOPSTART BV

Isaac Newton Institute for Mathematical Sciences

RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

BAYER CROPSCIENCE AG

UNIVERSITEIT UTRECHT

TISSUEGNOSTICS GMBH

Project information

Grant agreement ID: 642866

Status

Closed project

  • Start date

    1 January 2015

  • End date

    31 December 2018

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 866 665,32

  • EU contribution

    € 3 866 665,32

Coordinated by:

UNIVERSITAETSKLINIKUM AACHEN

Germany