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Mastering skills in the training Network for attention deficit hyperactivity and autism spectrum Disorders

Objective

Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are frequent, chronic and highly heritable neurodevelopmental disorders. Despite their societal importance, progress in understanding disease biology has been slow and no curative treatment options are available.
The pan-European training network MiND aims to educate a new generation of researchers in the field of neurodevelopmental disorders, through innovation-oriented research combined with highly interdisciplinary and intersectoral international training.
Research and training in MiND span state-of-the-art topics in the fields of ADHD, ASD and their yet un-investigated overlap. We combine advanced (epi-)genetics approaches with bioinformatics and develop novel cell and animal models of increasing complexity to understand pathomechanisms. Integrated with research in large human DNA-neuroimaging-cognition data sets, we push forward the understanding of the biology leading from gene to cognition and disease. Our mechanistic work is embedded in a framework exploring alternative disease definitions for ADHD and ASD across the lifespan and working towards improved treatment: we use novel cognitive assessments, we probe the microbiome for dietary interventions reducing symptoms and evaluate mindfulness training as non-pharmacological treatment options, in addition to developing new compounds for pharmacological treatment optimization and individualization. The strategic collaboration of world-leading academic groups, research-intensive commercial enterprises and patient organisations will deliver 15 young, scientifically excellent researchers which are optimally prepared for private sector and academic careers.
MiND can be expected to impact patients and society by improving our understanding of disease biology, by developing novel diagnostic and treatment strategies, and by raising awareness for the necessity of research of neurodevelopmental disorders from childhood to adulthood.

Coordinator

STICHTING KATHOLIEKE UNIVERSITEIT

Address

Geert Grooteplein Noord 9
6525 Ez Nijmegen

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 766 122,84

Participants (12)

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STICHTING KARAKTER

Netherlands

EU Contribution

€ 255 374,28

UNIVERSITY OF LEICESTER

United Kingdom

EU Contribution

€ 273 287,88

KING'S COLLEGE LONDON

United Kingdom

EU Contribution

€ 478 253,79

KAROLINSKA INSTITUTET

Sweden

EU Contribution

€ 263 659,32

UNIVERSITAT DE BARCELONA

Spain

EU Contribution

€ 247 872,96

BRAINGAZE SL

Spain

EU Contribution

€ 123 936,48

FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA

Spain

EU Contribution

€ 123 936,48

EUROFINS MEDIGENOMIX GMBH

Germany

EU Contribution

€ 62 304,12

JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN

Germany

EU Contribution

€ 436 128,84

UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT

Germany

EU Contribution

€ 124 608,24

UNIVERSITETET I BERGEN

Norway

EU Contribution

€ 572 550,48

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

EU Contribution

€ 185 904,72

Partners (9)

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RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK

Scandinavian Development Services

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Aktogen Limited

BRAIN INNOVATION BV

PRESTWICK CHEMICAL SAS

NIZO FOOD RESEARCH BV

ADHD-Europe

AUTISME-EUROPE AISBL

Project information

Grant agreement ID: 643051

Status

Closed project

  • Start date

    1 January 2015

  • End date

    31 December 2018

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 913 940,43

  • EU contribution

    € 3 913 940,43

Coordinated by:

STICHTING KATHOLIEKE UNIVERSITEIT

Netherlands