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Smart Phone for Disease Detection from Exhaled Breath

Smart Phone for Disease Detection from Exhaled Breath

Objective

Screening for early detection of a disease is required to reveal groups of individuals from the general population in whom the likelihood of the disease is increased and who could benefit from further medical evaluation. The ideal screening test is high-accuracy, low-cost, non-invasive, easily repeatable, effortlessly operated by a lay-person and has minimal impact on the person’s daily activities.. In the SNIFFPHONE project, we aim to tackle these requirements by integrating heterogeneous micro- and nano-technologies into autonomous smart system that can be attached to a mobile phone and analyze disease markers from exhaled breath. In this approach, an interaction between breath sample and a miniaturized array of highly sensitive nanomaterial-based chemical sensors is recorded, stored and pre-processed by integrated miniature on-chip microfluidics and electronics, and then the relevant electrical signals are transferred wirelessly via the mobile phone’s internet to an external server. Statistical pattern recognition methods are then applied on the received data and a clinical report including the screening results is sent back to the designated receiver (e.g., specialist, family doctor) in case of positive result is revealed. SNIFFPHONE represents a new concept addressing major societal challenges in health and well-being of the general population, while taking into account constituent ethical and security aspects. The SNIFFPHONE end-product will integrate functionalities that are relevant to the health screening applications with decreased size (x30-40), decreased costs (x150), increased predictive and cognitive functions and full autonomy with energy management as well as with operation/use management. Besides the R&D and clinical units, the SNIFFPHONE project will involve four European SMEs and one big industrial company, thus establishing European competitive ecosystems for the design and commercialization of innovative miniaturized smart systems.
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Coordinator

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

Address

Senate Building Technion City
32000 Haifa

Israel

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 298 379,18

Participants (10)

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SIEMENS AKTIENGESELLSCHAFT

Germany

EU Contribution

€ 249 373,98

Teknologian tutkimuskeskus VTT Oy

Finland

EU Contribution

€ 794 987,50

TEKNOLOGIAN TUTKIMUSKESKUS VTT

Finland

UNIVERSITAET INNSBRUCK

Austria

EU Contribution

€ 410 000

LATVIJAS UNIVERSITATE

Latvia

EU Contribution

€ 599 250

MICROFLUIDIC CHIPSHOP GMBH

Germany

EU Contribution

€ 498 750

NanoVation-GS

Israel

EU Contribution

€ 407 393,75

CELLIX LIMITED

Ireland

EU Contribution

€ 651 470,18

JLM INNOVATION GMBH

Germany

EU Contribution

€ 641 850,41

SIEMENS HEALTHCARE GMBH

Germany

EU Contribution

€ 255 000

Project information

Grant agreement ID: 644031

Status

Closed project

  • Start date

    15 February 2015

  • End date

    14 February 2019

Funded under:

H2020-EU.2.1.1.1.

  • Overall budget:

    € 5 806 455

  • EU contribution

    € 5 806 455

Coordinated by:

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY

Israel