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Integrated Spectrometers for Spectral Tissue Sensing

Integrated Spectrometers for Spectral Tissue Sensing

Objective

Image-guided needle procedures - such as taking biopsies in screening cancerous tumours - are becoming increasingly important in clinical practice. Today, physicians are severely hampered by the lack of precision in positioning the needle tip. Real-time tissue-characterization feedback at the needle tip during these procedures can significantly improve the outcome of diagnosis and treatment, and reduce the cost of oncology treatment. Spectral tissue sensing using photonic needles has the promise to be a valuable diagnostic tool for screening tumours, as shown by several clinical trials. However, for widespread adoption the cost and size of these photonic needle systems - in particular the spectrometer console - needs to be improved dramatically. The realization of a low-cost miniature system is limited by three key challenges:
• Broadband (VIS+NIR) illumination
• Broadband (VIS+NIR) sensitivity
• Integration of the system
InSPECT will address these challenges by developing and integrating photonic building blocks for low-cost miniaturized spectral tissue sensing devices. This involves the realization of a miniature broadband (400-1700 nm) solid-state light source, based on phosphor and quantum-dot converted LEDs, and the realization of a miniature low-cost integrated VIS+NIR spectrometer. For the spectrometer integration we will follow 2 approaches:
• The micro-spectrometer, a moderate risk approach based on the miniaturisation and monolithic integration of diffractive dispersive elements and VIS+NIR photo-detectors in a small volume (cubic inch) device, and
• The nano-spectrometer, a higher risk approach in which the spectrometer function is realized in a photonic integrated circuit (PIC) based on transparent SiO/SiN waveguide technology.
This is a unique, novel, and timely approach to realize the key photonics building blocks for low-cost miniature spectrometers that will drive the adoption of spectral sensing in applications that were not accessible before.

Coordinator

PHILIPS ELECTRONICS NEDERLAND B.V.

Address

Boschdijk 525
5621 Jg Eindhoven

Netherlands

Activity type

Other

EU Contribution

€ 1 011 583

Participants (9)

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AVANTES BV

Netherlands

EU Contribution

€ 247 766

VRIJE UNIVERSITEIT BRUSSEL

Belgium

EU Contribution

€ 384 875

XENICS NV

Belgium

EU Contribution

€ 542 110

ANTERYON BV

Netherlands

EU Contribution

€ 287 265

XIO PHOTONICS BV

Netherlands

LIONIX INTERNATIONAL BV

Netherlands

EU Contribution

€ 689 250

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Germany

EU Contribution

€ 540 861

AIFOTEC AG

Germany

EU Contribution

€ 195 875

PHILIPS MEDICAL SYSTEMS NEDERLAND BV

Netherlands

EU Contribution

€ 243 875

Project information

Grant agreement ID: 644483

  • Start date

    1 January 2015

  • End date

    31 March 2018

Funded under:

H2020-EU.2.1.1.6.

  • Overall budget:

    € 4 143 461,25

  • EU contribution

    € 4 143 460

Coordinated by:

PHILIPS ELECTRONICS NEDERLAND B.V.

Netherlands