Objective The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to develop a platform of “green” chemoenzymatic methods for the production of high value active pharmaceutical ingredients – both those currently on the market, and those in development pipelines of the Pharma industry. The partners will exemplify the use of the platform through its application in the production of 4 drugs currently on the market – namely Duloxetine, Atomexetine, Ramosetron and Paricalcitol.In order to achieve this objective the proposal brings together 3 partners with complementary skills:Kelada Pharmachem: Phase transfer catalysis/organo catalysis/scale-up of chemical processesCerbios Pharma: Biocatalysis and fermentation methodologies for drug productionIC-CNR: Protein crystallography and enzymatic engineering Fields of science medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsnatural scienceschemical sciencesorganic chemistryketonesnatural sciencesearth and related environmental sciencesgeologymineralogycrystallographynatural scienceschemical sciencesorganic chemistryalcoholsengineering and technologyindustrial biotechnologybioprocessing technologiesfermentation Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge Topic(s) MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Call for proposal H2020-MSCA-RISE-2014 See other projects for this call Funding Scheme MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) Coordinator CONSIGLIO NAZIONALE DELLE RICERCHE Net EU contribution € 162 000,00 Address PIAZZALE ALDO MORO 7 00185 Roma Italy See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 162 000,00 Participants (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all KELADA PHARMACHEM LIMITED Ireland Net EU contribution € 72 000,00 Address 161 RATHMINES ROAD LOWER A94 Dublin See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ireland Eastern and Midland Dublin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 72 000,00 Partners (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. CERBIOS-PHARMA SA Switzerland Net EU contribution € 0,00 Address VIA FIGINIO 6 6917 BARBENGO See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Schweiz/Suisse/Svizzera Ticino Ticino Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data