Objective Infertility is a heavy social issue,experienced by nearly one in six couples during reproductive lifetime.In Vitro Fertilization (IVF) is growing 8-10% p.a.,to 1.5 million therapy cycles and 7.5 billion dollars in 2013.Despite stressful and costly procedures,IVF success rate is low (15-20% births/cycle),leaving big opportunities for innovation and process optimization.EMBRYON introduces to IVF clinics and specialists a last-generation diagnostic-imaging system,favoring better outcomes through deeper,smarter analysis of clinical images.It merges tailored image-processing software and algorithms,patented by ACS,with a high-end commercial IVF microscope.A prototype is under validation with top clinics in Italy and Switzerland,supported by Nikon Instruments (global leader in IVF microscopy).EMBRYON improves the key success factor of any IVF procedure:the identification of 1-2 embryos with best “pregnancy potential” to be transferred in utero,amongst 5-10 generated in vitro.EMBRYON’s precision is double than current handcrafted approaches,favoring higher success rates.It is safer (100% not invasive),thus simpler to certify and adopt,fully compliant with ethical regulation,easier to use (no change to lab procedures) and cheaper than similar products.Key innovations1. Automated deep scan of embryo shape,overcoming today’s subjective and approximate observations carried by the physician2. Proprietary algorithms for the measurement of complex morphological patterns,strong predictors of potentialSales forecasts are 1200-1400 units (40-45 M€ gross revenues) by 2020 in Europe and US,favored by:- High reactivity of the IVF sector (scientists/patients) to validated solutions improving outcomes- Commercial partnership with a global IVF microscopy leaderIn Ph1 we’ll finalize and publish the ongoing clinical studies and make a deep market analysis for Europe-USIn Ph2 we plan CE/FDA clearance,WW extension of patents,3 trials in Europe-US,set-up of newco and sales org Fields of science medical and health sciencesclinical medicinegynaecologyreproductive medicinesocial sciencessociologysocial issuesnatural sciencesphysical sciencesopticsmicroscopymedical and health sciencesclinical medicineobstetricsmedical and health sciencesclinical medicineembryology Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.3. - Treating and managing disease Topic(s) PHC-12-2014-1 - Clinical research for the validation of biomarkers and/or diagnostic medical devices Call for proposal H2020-SMEInst-2014-2015 See other projects for this call Sub call H2020-SMEINST-1-2014 Funding Scheme SME-1 - SME instrument phase 1 Coordinator ADVANCED COMPUTER SYSTEMS A.C.S. SRL Net EU contribution € 50 000,00 Address VIA DELLA BUFALOTTA 378 00139 ROMA Italy See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Centro (IT) Lazio Roma Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 71 429,00
