CORDIS
EU research results

CORDIS

English EN

Bio-derived HIgh Value polymers through novel Enzyme function

Objective

Recent advances in systems-level study of cells and organisms have revealed the enormous potential to live more sustainably through better use of biological processes. Plants sustainably synthesize the most abundant and diverse materials on Earth. By applying recent advances in life science technology, we can better harness renewable plant resources and bioconversion processes, to develop environmentally and politically sustainable human enterprise and lifestyles. At the same time, the global market for high-value biochemicals and bioplastics from forest and agricultural sources is rapidly increasing, which presents new opportunities for forest and agricultural sectors.

The overall aim of BHIVE is to illuminate uncharted regions of genome and metagenome sequences to discover entirely new protein families that can be used to sustainably synthesize novel, high-value biomaterials from renewable plant resources. The approach will include three parallel research thrusts: 1) strategic analysis of transcriptome and metagenome sequences to identify proteins with entirely unknown function relevant to biomass (lignocellulose) transformation, 2) mapping of uncharted regions within phylogenetic trees of poorly characterized enzyme families with recognized potential to modify the chemistry and biophysical properties of plant polysaccharides, and 3) the design and development of novel enzyme screens to directly address the increasing limitations of existing assays to uncover entirely new protein functions. BHIVE will be unique in its undivided focus on characterizing lignocellulose-active proteins encoded by the 30-40% of un-annotated sequence, or genomic “dark matter”, typical of nearly all genome sequences. In this way, BHIVE tackles a key constraint to fully realizing the societal and environmental benefits of the genomics era.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Host institution

AALTO KORKEAKOULUSAATIO SR

Address

Otakaari 1
02150 Espoo

Finland

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 977 781

Beneficiaries (1)

Sort alphabetically

Sort by EU Contribution

Expand all

AALTO KORKEAKOULUSAATIO SR

Finland

EU Contribution

€ 1 977 781

Project information

Grant agreement ID: 648925

Status

Ongoing project

  • Start date

    1 September 2015

  • End date

    31 August 2020

Funded under:

H2020-EU.1.1.

  • Overall budget:

    € 1 977 781

  • EU contribution

    € 1 977 781

Hosted by:

AALTO KORKEAKOULUSAATIO SR

Finland