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Development of a new immunoassay platform based on porous antibody microparticles

Development of a new immunoassay platform based on porous antibody microparticles

Objective

Rapid and sensitive analyte determination in small volumes is one of the main tasks in modern diagnostics for the development of miniaturized in vitro test systems. This is critically important for both health and environmental diagnostics. The traditional approach (ELISA) is a time-consuming multistep process with sensitivity limitations due to usually used planar supports for detection. In this project we intend to develop a new approach for biosensing based on porous antibody microparticles. For this purpose, the combination of a new technique to assemble porous particles at mild conditions (host know-how) and highly sensitive ELISA-based detection system (applicant know-how) will be used. The porous particles will work as a platform with two crucial features: i) specific immunochemical reactions are realized on highly developed particle surface, ii) separation and detection in small volumes (micrometer dimensions). We believe that the proposed approach may open new avenues in future for effective diagnostics.
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Coordinator

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Address

Hansastrasse 27c
80686 Munchen

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 159 460,80

Project information

Grant agreement ID: 657079

  • Start date

    1 October 2015

  • End date

    30 September 2017

Funded under:

H2020-EU.1.3.2.

  • Overall budget:

    € 159 460,80

  • EU contribution

    € 159 460,80

Coordinated by:

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Germany