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MASS Spectrometry TRaining network for Protein Lipid adduct ANalysis

Project information

Grant agreement ID: 675132

Status

Closed project

  • Start date

    1 October 2015

  • End date

    30 September 2019

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 545 010,72

  • EU contribution

    € 3 545 010,72

Coordinated by:

ASTON UNIVERSITY

United Kingdom

Objective

MASSTRPLAN will train the next generation of interdisciplinary research leaders in advanced molecular analytical techniques to detect oxidized phospholipids & proteins in biological & clinical samples, evaluate their biochemical roles in inflammation, and translate these findings to develop new diagnostic tools.
Chronic inflammatory diseases such as diabetes, cardiovascular disease (CVD) & cancer are major causes of mortality and cost the EU economy dearly in healthcare and lost working time; CVD alone is estimated to be responsible for 47% of deaths and to cost the EU €196 billion a year. Scientists able to develop advanced analytical tools for detecting oxidative biomolecule modifications and assessing their contribution to cell dysfunction & disease are urgently needed.
The objectives of MASSTRPLAN are to 1) train early stage researchers (ESRs) in advanced and novel chromatography, mass spectrometry, and complementary techniques including microscopy and bioinformatics to detect challenging heterogeneous biomolecule modifications and determine their functional effects; 2) give ESRs a broad perspective on relevance & mechanisms of oxidative modifications in pathophysiology and biotechnology; 3) enable ESRs trained in technology development to engage effectively with the clinical sector; and 4) train ESRs in translational and development skills to produce new protocols, materials and commercializable diagnostic tools.
The ETN will achieve this by bringing together 10 beneficiaries and 15 partners from academic, industrial and healthcare organizations working in analytical, bioinformatic, biological, clinical & biotech fields to provide multidisciplinary, cross-sector training. Extensive mobility, industrial secondments and network-wide training will yield a cohort of analytical scientists with the unique theoretical, technological, and entrepreneurial skill set to yield new understanding of oxidative inflammatory disorders, leading to better tools and therapies.

Coordinator

ASTON UNIVERSITY

Address

Aston Triangle
B4 7et Birmingham

United Kingdom

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 546 575,76

Participants (10)

UNIVERSIDADE DE AVEIRO

Portugal

EU Contribution

€ 476 712,72

UNIVERSITAET LEIPZIG

Germany

EU Contribution

€ 498 432,96

UNIVERSITA DEGLI STUDI DI MILANO

Italy

EU Contribution

€ 258 061,32

VIB VZW

Belgium

EU Contribution

€ 250 560

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Spain

EU Contribution

€ 495 745,92

CENTRO CARDIOLOGICO MONZINO

Italy

EU Contribution

€ 258 061,32

INSTITUTO PORTUGUES DO SANGUE E DA TRANSPLANTACAO IP

Portugal

MOLOGIC LTD

United Kingdom

EU Contribution

€ 273 287,88

THERMO FISHER SCIENTIFIC (BREMEN) GMBH

Germany

EU Contribution

€ 249 216,48

CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA E.P.E.

Portugal

EU Contribution

€ 238 356,36

Partners (15)

AB SCIEX UK LIMITED

United Kingdom

Waters Corp (Micromass UK ltd)

United Kingdom

UNICAM SISTEMAS ANALITICOS

Portugal

DSM FOOD SPECIALTIES BV

Netherlands

Antec Leyden BV

Netherlands

Cayman Chemical Company

United States Minor Outlying Islands

CELL2B ADVANCED THERAPEUTICS SA

Portugal

DSM Nutritional Products Ltd

Switzerland

Red Española de Microscopía Óptica

Spain

Achucarro Basque Center for Neurosc

Spain

Universitatsklinikum Leipzig

Germany

Centro Hospitalar Baixo Vouga

Portugal

ELSEVIER BV

Netherlands

European Proteomics Association

Germany

Society for Free Radical Research Europe

United Kingdom

Project information

Grant agreement ID: 675132

Status

Closed project

  • Start date

    1 October 2015

  • End date

    30 September 2019

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 545 010,72

  • EU contribution

    € 3 545 010,72

Coordinated by:

ASTON UNIVERSITY

United Kingdom