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Targeted small-molecule Stabilisation of Protein-Protein Interactions

Project information

Grant agreement ID: 675179

Status

Closed project

  • Start date

    1 February 2016

  • End date

    31 January 2020

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 342 323,49

  • EU contribution

    € 3 342 323,49

Coordinated by:

TECHNISCHE UNIVERSITEIT EINDHOVEN

Netherlands

Objective

The goal of the TASPPI European Training Network (ETN) is the establishment of a highly interdisciplinary research and educational training platform for early stage scientists in the Chemical Life Sciences to overcome the inherent boundaries between academia and industry and to increase their employability in both areas. To this end we have teamed up in a consortium comprising 5 partners from industry (AstraZeneca, GlaxoSmithKline, UCB, Lead Disocvery Center, Taros Chemicals) and 6 partners from academia (Universities of Dundee, Eindhoven, Leeds, Lille, Prague, and Siena). The scientific objective of the multi-sectorial Training Network is the development and implementation of a multidisciplinary technology platform bringing together structural molecular biology, chemical biology, cell biology, synthetic chemistry, and medicinal chemistry for the identification of Small-molecule Stabilizers of Protein-Protein Interactions (PPIs) as a novel class of therapeutic agents and basic research tool compounds. With this new technological approach we aim to address a number of unmet medical needs in the areas Cancer, Neurodegenerative Diseases (Alzheimer’s, Parkinson’s), Pulmonary Diseases, Inflammation and Metabolic Diseases (Diabetes).

Coordinator

TECHNISCHE UNIVERSITEIT EINDHOVEN

Address

Groene Loper 3
5612 Ae Eindhoven

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 766 122,84

Participants (10)

UNIVERSITY OF LEEDS

United Kingdom

EU Contribution

€ 273 287,88

UNIVERZITA KARLOVA

Czechia

EU Contribution

€ 232 422,48

UNIVERSITY OF DUNDEE

United Kingdom

EU Contribution

€ 273 287,88

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

France

EU Contribution

€ 262 875,60

UNIVERSITA DEGLI STUDI DI SIENA

Italy

EU Contribution

€ 258 061,32

LEAD DISCOVERY CENTER GMBH

Germany

EU Contribution

€ 249 216,48

ASTRAZENECA AB

Sweden

EU Contribution

€ 527 318,64

TAROS CHEMICALS GMBH & CO KG

Germany

EU Contribution

€ 249 216,48

UCB BIOPHARMA SRL

Belgium

CELLTECH R&D LIMITED

United Kingdom

EU Contribution

€ 250 513,89

Partners (1)

GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD.

United Kingdom

Project information

Grant agreement ID: 675179

Status

Closed project

  • Start date

    1 February 2016

  • End date

    31 January 2020

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 342 323,49

  • EU contribution

    € 3 342 323,49

Coordinated by:

TECHNISCHE UNIVERSITEIT EINDHOVEN

Netherlands