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European Network linking informatics and genomics of helper T cells

Objective

ENLIGHT-TEN is a European Network Linking Informatics and Genomics of Helper T cells: our mission is to provide cross-disciplinary training in cellular immunology and big data analysis such that we train a new generation of researchers to fully exploit the power of emerging technological platforms. Our network of TEN beneficiaries combines T cell expertise with state-of-the-art technologies such as next generation sequencing (NGS), bioinformatics, multi-colour flow cytometry, preclinical models and tailored genome editing. Trainees will acquire a comprehensive knowledge in T cell immunology and the capacity to generate and interrogate big data sets as well as expertise in identifying novel biomarkers and developing therapeutic concepts. As such the training programme will provide an ideal stepping-stone for creative and innovative early stage researchers (ESRs) to enter and strengthen Europe’s academia as well as pharmaceutical and bioinformatics companies.
The research focus of the network lies in the identification of extrinsic and intrinsic factors that control development, differentiation and plasticity of helper T cell subsets with particular emphasis on how T cell differentiation impacts on human diseases. The generation of large data sets is an emerging and challenging field, and there is high demand in both the academic sector as well as pharmaceutical companies for researchers to be able to analyse, integrate and exploit this rich source of information. ENLIGHT-TEN will combine the individual strengths of innovative laboratories and enterprises from complementary disciplines to provide unique interdisciplinary training for 13 ESRs, placing them at the forefront of this emerging field. Trainees will be empowered to perform cutting-edge analysis of the steadily increasing number of different T cell subsets, which play highly diverse and critical roles in the development of autoimmune diseases, making them a key target for pharmaceutical companies.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH

Address

Inhoffenstrasse 7
38124 Braunschweig

Germany

Activity type

Research Organisations

EU Contribution

€ 498 432,96

Participants (10)

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UNIVERSITY COLLEGE LONDON

United Kingdom

EU Contribution

€ 273 287,88

MEDIZINISCHE UNIVERSITAET WIEN

Austria

EU Contribution

€ 255 934,08

Bayer Pharma AG

Germany

EU Contribution

€ 249 216,48

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Germany

INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES

Portugal

EU Contribution

€ 476 712,72

THE BABRAHAM INSTITUTE

United Kingdom

EU Contribution

€ 546 575,76

TURUN YLIOPISTO

Finland

EU Contribution

€ 269 145,36

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

EU Contribution

€ 262 875,60

QIAGEN AARHUS AS

Denmark

EU Contribution

€ 249 216,48

GENOME RESEARCH LIMITED

United Kingdom

EU Contribution

€ 273 287,88

Partners (6)

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Abcam plc

United Kingdom

AFFIRIS AG

Austria

CRISPR Therapeutics Limited

United Kingdom

EAGLE GENOMICS LIMITED

United Kingdom

Genomatix Software GmbH

Germany

NOVIMMUNE SA

Switzerland

Project information

Grant agreement ID: 675395

Status

Closed project

  • Start date

    1 October 2015

  • End date

    30 September 2019

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 354 685,32

  • EU contribution

    € 3 354 685,20

Coordinated by:

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH

Germany