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Promoting SINgle cell GEnomics to explore the ecology and evolution of hidden microeuKaryotes

Promoting SINgle cell GEnomics to explore the ecology and evolution of hidden microeuKaryotes

Objective

Environmental microbial surveys have revealed a remarkable diversity of microeukaryotic life in most ecosystems, the majority of which had previously escaped detection. From an ecological point of view this work highlighted our ignorance of critical microbial players in natural environmental processes, including primary production, biogeochemical cycling and trophic interactions such as parasitism and grazing. Consequently, our understanding of community function is partial, limiting our ability to study environmental change. While, from an evolutionary perspective, we are missing major components of the Tree of Life giving rise to a fragmented understanding of how major cellular functions have evolved. Single cell genomics (SCG), including single cell transcriptomics, is an emerging technology that has the potential to retrieve genomic information from individual uncultured microbes recovered directly from natural environments and promises to provide new tools to investigate microeukaryotes in unparalleled detail. The aim of this ITN is therefore to train a new generation of scientists with the highest expertise, in SCG, from the initial stages of cell sorting to genome sequencing and gene annotation, to the full exploitation of the data obtained. Such progress will allow the European research community for the first time to address critical ecological and evolutionary questions. SINGEK will drive training through research by both local and network-wide activities, secondments, and workshops, and by establishing an environment that extends far beyond each partner team. This training environment will also provide the transferable skills essential for successful career development. This network of well connected and highly qualified scientists with expertise in eukaryotic SCG will be ready to implement this technology beyond ecology and evolution to other fields such as biomedicine or biotechnology driving innovation across the EU.

Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Address

Calle Serrano 117
28006 Madrid

Spain

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 881 326,08

Participants (8)

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UPPSALA UNIVERSITET

Sweden

EU Contribution

€ 527 318,64

FUNDACIO CENTRE DE REGULACIO GENOMICA

Spain

EU Contribution

€ 247 872,96

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

France

EU Contribution

€ 788 626,80

VIB

Belgium

EU Contribution

€ 250 560

THE UNIVERSITY OF EXETER

United Kingdom

EU Contribution

€ 546 575,76

LUNDS UNIVERSITET

Sweden

EU Contribution

€ 263 659,32

THE UNIVERSITY OF LIVERPOOL

United Kingdom

EU Contribution

€ 273 287,88

ASCIDEA COMPUTATIONAL BIOLOGY SOLUTIONS SL

Spain

EU Contribution

€ 110 165,76

Partners (7)

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GREENSEA SAS

FLUIGENT SA

THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS

MUSEUM NATIONAL D'HISTOIRE NATURELLE

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

WriteScience

Plàncton, Divulgació I Serveis Marins S.C.P.

Project information

Grant agreement ID: 675752

Status

Ongoing project

  • Start date

    1 January 2016

  • End date

    31 May 2020

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 889 393,20

  • EU contribution

    € 3 889 393,20

Coordinated by:

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Spain