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Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders

Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders

Objective

RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious objectives of RUBICON are to increase our knowledge of the mechanisms underlying diverse connective tissue disorders, identify commonalities and targetable pathways, and reinforce multidisciplinary awareness in this fundamental research field.
Researchers involved in secondments between RUBICON participants will investigate genetic determinants, circadian clock, extracellular matrix components, soluble biochemical factors and intracellular signalling pathways, ER stress and oxidative components involved in connective tissue homeostasis and pathogenesis. Extensive training during secondments will include new technologies and innovation, study design, interdisciplinary laboratory research, data analysis, research management, ethics in animal and human studies, and development of scientific and communication skills. All participating laboratories will ensure attractive working conditions in excellent and internationally recognised institutions, equipped with state-of-the-art instruments and excellent core facilities. Webinars, courses and meetings will provide additional opportunities for training and networking, also be open to external participants.
RUBICON is a unique interdisciplinary network including cell biologists, molecular biologists, animal biologists, morphologists, geneticists, biochemists and clinicians who will cross-fertilise their respective research fields. The long-term goal of RUBICON is to consolidate a class of young scientists to secure future developments in the connective tissue arena and create a solid basis for further collaboration in this field.

Coordinator

UNIVERSITA DEGLI STUDI DELL'AQUILA

Address

Piazza Vincenzo Rivera 1
67100 L Aquila

Italy

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 171 000

Participants (4)

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UNIVERSITY OF NEWCASTLE UPON TYNE

United Kingdom

EU Contribution

€ 90 000

THE UNIVERSITY OF MANCHESTER

United Kingdom

EU Contribution

€ 144 000

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Netherlands

EU Contribution

€ 94 500

REGION HOVEDSTADEN

Denmark

EU Contribution

€ 108 000

Partners (5)

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UNIVERSITY OF CAPE TOWN

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

ANNA UNIVERSITY CHENNAI

THE UNIVERSITY OF HONG KONG

MURDOCH CHILDRENS RESEARCH INSTITUTE

Project information

Grant agreement ID: 690850

Status

Ongoing project

  • Start date

    1 January 2016

  • End date

    31 December 2019

Funded under:

H2020-EU.1.3.3.

  • Overall budget:

    € 877 500

  • EU contribution

    € 607 500

Coordinated by:

UNIVERSITA DEGLI STUDI DELL'AQUILA

Italy