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Breaking the Nonuniqueness Barrier in Electromagnetic Neuroimaging

Objective

By combining accurate magnetic measurements of neural activity with near-simultaneous high-definition measurements of cerebral structure – provided by novel methods in ultra-low-field magnetic resonance imaging (ULF MRI ) – we will be able to image the dynamics of human brain function at unprecedented resolution and reliability. BREAKBEN will achieve a revolution in neuroimaging; we aim at breaking the barrier for measurement of neuronal currents by ULF MRI (neural current imaging; NCI) as well as breaking the nonuniqueness barrier for magnetoencephalography (MEG) by combining it with ULF MRI and accurately presented a priori information. A key aspect in utilizing the a priori information is injected current density imaging (CDI), which will inform us about the individual conductivity structure of the head. Using novel verification and validation approaches, we will demonstrate the unique advantages of these multimodal techniques. These breakthroughs will result in completely different workflows in brain imaging, also suitable for clinical use. We believe that we are at the edge of a qualitative technology jump with ULF MRI, its applications and combinations. This will lead to a wealth of new applications and revolutionize the way we do magnetism-based measurements of the nervous system. Europe has the unique chance to lead this revolution.

Field of science

  • /medical and health sciences/clinical medicine/radiology/medical imaging/magnetic resonance imaging

Call for proposal

H2020-FETOPEN-2014-2015-RIA
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

AALTO KORKEAKOULUSAATIO SR
Address
Otakaari 1
02150 Espoo
Finland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 959 030,50

Participants (6)

MEGIN OY
Finland
EU contribution
€ 413 735
Address
Siltasaarenkatu 18-20 A
00530 Helsinki
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ
Finland
EU contribution
€ 187 646,25
Address
Stenbackinkatu 9
00029 Helsinki
Activity type
Research Organisations
PHYSIKALISCH-TECHNISCHE BUNDESANSTALT
Germany
EU contribution
€ 779 268,75
Address
Bundesallee 100
38116 Braunschweig
Activity type
Research Organisations
TECHNISCHE UNIVERSITAET ILMENAU
Germany
EU contribution
€ 442 871,25
Address
Ehrenbergstrasse 29
98693 Ilmenau
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI GABRIELE D'ANNUNZIO DI CHIETI-PESCARA
Italy
EU contribution
€ 440 100
Address
Via Dei Vestini 31
66013 Chieti
Activity type
Higher or Secondary Education Establishments
Teknologian tutkimuskeskus VTT Oy
Finland
EU contribution
€ 776 141,25
Address
Vuorimiehentie 3
02150 Espoo
Activity type
Research Organisations