CORDIS
EU research results

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Innovative Dermatology Healthcare based on Label-Free Spectral Optoacoustic Mesoscopy

Project information

Grant agreement ID: 687866

Status

Ongoing project

  • Start date

    1 March 2016

  • End date

    28 February 2021

Funded under:

H2020-EU.2.1.1.

  • Overall budget:

    € 4 595 125

  • EU contribution

    € 3 869 879,13

Coordinated by:

TECHNISCHE UNIVERSITAET MUENCHEN

Germany

Objective

Multispectral Optoacoustic Tomography (MSOT) brings a revolution to bio-optical imaging. Being insensitive to photon scattering, MSOT dramatically improves upon conventional bio-optic barriers by enabling (1) three-dimensional high-resolution optical imaging deep inside tissues (several millimetres to centimetres), by (2) high-scalability, ranging from optical-resolution microscopy to acoustic-resolution optical mesoscopy and macroscopy and by (3) novel label-free anatomical, physiological and molecular contrast at the tissue and single-cell-level, based on spectrally-resolved optical absorption. MSOT, originally supported by an ERC Advanced Award (2008) (TUM: Prof. Ntziachristos), is already commercialized by iThera Medical for macroscopy with systems sold around the world for small animal imaging. In parallel, ERC MSOT funding developed a mesoscopic implementation, termed raster-scan optoacoustic mesoscopy (RSOM), which has demonstrated innovative imaging capacity at 1-5mm depths.
Driven by leading dermatologists (TUM: Prof. Biedermann; SUR: Prof. Costanzo) and market leader SMEs in optoacoustic and ultrasound technology (iThera, Rayfos, Sonaxis), INNODERM will design and prototype a handheld, portable, scalable, label-free RSOM device for point-of care dermatology applications, based on recommendations developed under an ERC proof of concept grant (2013) on MSOT. INNODERM brings together key photonic & ultrasound technologies and will validate the technical and economic viability of RSOM in dermatology suites for fast diagnosis and skin disease monitoring. RSOM can go beyond the abilities of current optical or optoacoustic devices and offer a paradigm shift in dermatology imaging, substantiating successful business cases.

Coordinator

TECHNISCHE UNIVERSITAET MUENCHEN

Address

Arcisstrasse 21
80333 Muenchen

Germany

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 432 350

Participants (5)

SONAXIS SA

France

EU Contribution

€ 471 238,25

RAYFOS LTD

United Kingdom

EU Contribution

€ 496 133,75

ITHERA MEDICAL GMBH

Germany

EU Contribution

€ 724 868,38

UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA

Italy

HUMANITAS UNIVERSITY

Italy

EU Contribution

€ 745 288,75

Project information

Grant agreement ID: 687866

Status

Ongoing project

  • Start date

    1 March 2016

  • End date

    28 February 2021

Funded under:

H2020-EU.2.1.1.

  • Overall budget:

    € 4 595 125

  • EU contribution

    € 3 869 879,13

Coordinated by:

TECHNISCHE UNIVERSITAET MUENCHEN

Germany