Objective This project addresses the scientific, technological and clinical problem of recovery of hand function after amputation. Despite decades of research and development on artificial limbs and neural interfaces, amputees continue to use technology for powered prostheses developed over 40 years ago, namely myoelectric prostheses controlled via superficial electrodes. These devices do not purposely provide sensory feedback and are known for their poor functionality, controllability and sensory feedback, mainly due to the use of surface electrodes.The consortium has pioneered the use of osseointegration as a long-term stable solution for the direct skeletal attachment of limb prostheses. This technology aside from providing an efficient mechanical coupling, which on its own has shown to improve prosthesis functionality and the patient’s quality of life, can also be used as a bidirectional communication interface between implanted electrodes and the prosthetic arm. This is today the most advanced and unique technique for bidirectional neuromuscular interfacing, suited for the upper limb amputees, which was proven functional in the long term.The goal of the DeTOP project is to push the boundaries of this technology –made in Europe– to the next TRL and to make it clinically available to the largest population of upper limb amputees, namely transradial amputees. This objective will be targeted by developing a novel prosthetic hand with improved functionality, smart mechatronic devices for safe implantable technology, and by studying and assessing paradigms for natural control (action) and sensory feedback (perception) of the prosthesis through the implant. The novel technologies and findings will be assessed by three selected patients, implanted in a clinical centre.DeTOP bridges several currently disjointed scientific fields and is therefore critically dependent on the collaboration of engineers, neuroscientists and clinicians. Fields of science medical and health sciencesmedical biotechnologyimplants Keywords Upper limb prosthetics Programme(s) H2020-EU.2.1.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT) Main Programme Topic(s) ICT-24-2015 - Robotics Call for proposal H2020-ICT-2015 See other projects for this call Funding Scheme RIA - Research and Innovation action Coordinator SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO S ANNA Net EU contribution € 778 050,00 Address PIAZZA MARTIRI DELLA LIBERTA 33 56127 Pisa Italy See on map Region Centro (IT) Toscana Pisa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 778 050,00 Participants (9) Sort alphabetically Sort by Net EU contribution Expand all Collapse all GOETEBORGS UNIVERSITET Sweden Net EU contribution € 517 050,00 Address VASAPARKEN 405 30 Goeteborg See on map Region Södra Sverige Västsverige Västra Götalands län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 517 050,00 PRENSILIA SRL Italy Net EU contribution € 412 973,75 Address VIA RINALDO PIAGGIO 32 56025 Pontedera Pi See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Centro (IT) Toscana Pisa Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 412 973,75 INTEGRUM AB Sweden Net EU contribution € 1 419 450,00 Address KROKSLATTS FABRIKER 50 431 37 Molndal See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Södra Sverige Västsverige Västra Götalands län Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 419 450,00 LUNDS UNIVERSITET Sweden Net EU contribution € 538 827,50 Address Paradisgatan 5c 22100 Lund See on map Region Södra Sverige Sydsverige Skåne län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 538 827,50 CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT Switzerland Net EU contribution € 0,00 Address RUE JAQUET DROZ 1 2000 Neuchatel See on map Region Schweiz/Suisse/Svizzera Espace Mittelland Neuchâtel Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 894 637,50 UNIVERSITY OF ESSEX United Kingdom Net EU contribution € 528 370,00 Address WIVENHOE PARK CO4 3SQ Colchester See on map Region East of England Essex Essex Haven Gateway Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 528 370,00 ISTITUTO NAZIONALE ASSICURAZIONE INFORTUNI SUL LAVORO INAIL Italy Net EU contribution € 0,00 Address VIA IV NOVEMBRE 144 00187 Roma See on map Region Centro (IT) Lazio Roma Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 10 000,00 UNIVERSITA CAMPUS BIO MEDICO DI ROMA Italy Net EU contribution € 50 000,00 Address VIA ALVARO DEL PORTILLO 21 00128 Roma See on map Region Centro (IT) Lazio Roma Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 50 000,00 ISTITUTO ORTOPEDICO RIZZOLI Italy Net EU contribution € 15 800,00 Address VIA DI BARBIANO 1/10 40136 Bologna See on map Region Nord-Est Emilia-Romagna Bologna Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 15 800,00