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Dexterous Transradial Osseointegrated Prosthesis with neural control and sensory feedback

Objective

This project addresses the scientific, technological and clinical problem of recovery of hand function after amputation. Despite decades of research and development on artificial limbs and neural interfaces, amputees continue to use technology for powered prostheses developed over 40 years ago, namely myoelectric prostheses controlled via superficial electrodes. These devices do not purposely provide sensory feedback and are known for their poor functionality, controllability and sensory feedback, mainly due to the use of surface electrodes.

The consortium has pioneered the use of osseointegration as a long-term stable solution for the direct skeletal attachment of limb prostheses. This technology aside from providing an efficient mechanical coupling, which on its own has shown to improve prosthesis functionality and the patient’s quality of life, can also be used as a bidirectional communication interface between implanted electrodes and the prosthetic arm. This is today the most advanced and unique technique for bidirectional neuromuscular interfacing, suited for the upper limb amputees, which was proven functional in the long term.
The goal of the DeTOP project is to push the boundaries of this technology –made in Europe– to the next TRL and to make it clinically available to the largest population of upper limb amputees, namely transradial amputees. This objective will be targeted by developing a novel prosthetic hand with improved functionality, smart mechatronic devices for safe implantable technology, and by studying and assessing paradigms for natural control (action) and sensory feedback (perception) of the prosthesis through the implant. The novel technologies and findings will be assessed by three selected patients, implanted in a clinical centre.

DeTOP bridges several currently disjointed scientific fields and is therefore critically dependent on the collaboration of engineers, neuroscientists and clinicians.

Coordinator

SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO S ANNA
Net EU contribution
€ 778 050,00
Address
Piazza Martiri Della Liberta 33
56127 Pisa
Italy

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Region
Centro (IT) Toscana Pisa
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (9)

GOETEBORGS UNIVERSITET
Sweden
Net EU contribution
€ 517 050,00
Address
Vasaparken
405 30 Goeteborg

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Region
Södra Sverige Västsverige Västra Götalands län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
PRENSILIA SRL
Italy
Net EU contribution
€ 412 973,75
Address
Via Rinaldo Piaggio 32
56025 Pontedera Pi

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Centro (IT) Toscana Pisa
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
INTEGRUM AB
Sweden
Net EU contribution
€ 1 419 450,00
Address
Krokslatts Fabriker 50
431 37 Molndal

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Södra Sverige Västsverige Västra Götalands län
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
LUNDS UNIVERSITET
Sweden
Net EU contribution
€ 538 827,50
Address
Paradisgatan 5c
22100 Lund

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Region
Södra Sverige Sydsverige Skåne län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT
Switzerland
Net EU contribution
€ 0,00
Address
Rue Jaquet Droz 1
2000 Neuchatel

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Region
Schweiz/Suisse/Svizzera Espace Mittelland Neuchâtel
Activity type
Research Organisations
Other funding
€ 894 637,50
UNIVERSITY OF ESSEX
United Kingdom
Net EU contribution
€ 528 370,00
Address
Wivenhoe Park
CO4 3SQ Colchester

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Region
East of England Essex Essex Haven Gateway
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
ISTITUTO NAZIONALE ASSICURAZIONE INFORTUNI SUL LAVORO INAIL
Italy
Net EU contribution
€ 0,00
Address
Via Iv Novembre 144
00187 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 10 000,00
UNIVERSITA CAMPUS BIO MEDICO DI ROMA
Italy
Net EU contribution
€ 50 000,00
Address
Via Alvaro Del Portillo 21
00128 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
ISTITUTO ORTOPEDICO RIZZOLI
Italy
Net EU contribution
€ 15 800,00
Address
Via Di Barbiano 1/10
40136 Bologna

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Region
Nord-Est Emilia-Romagna Bologna
Activity type
Research Organisations
Other funding
€ 0,00