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Automated diagnostic platform, data management system and innovative communication tool, for improving the impact of malaria vector control interventions

Automated diagnostic platform, data management system and innovative communication tool, for improving the impact of malaria vector control interventions

Objective

Malaria is a life-threatening disease causing more than 500,000 deaths every year in sub-Saharan Africa. Prevention of the disease is best achieved by vector control which relies on the use of insecticides. Monitoring mosquito vector populations is an integral component of control programmes and a prerequisite for effective interventions. Several individual methods are used for this task, However, there are obstacles to their uptake, as well as challenges in organizing, interpreting and communicating vector control data.
We will develop a fully integrated and automated multiplex vector-diagnostic platform (LabDisk) for monitoring the species ID, the infection status of mosquitoes and the insecticide resistance profile of malaria vector populations. The system will provide sample-to-answer determinations, and it will perform genotyping at substantially lower cost, compared to the assays that are currently used in Africa.
The LabDisk will be interfaced with a Disease Data Management System (DDMS), custom made data management software which will collect data from routine entomological monitoring activities, store, and make available stratified information based on “user queries” in a standardized way.
The “GAME”, a modern ICT platform that employs interactive ways of communicating guidelines and exemplifying good practices of successful use of interventions in the health sector will be also employed, to teach operational end users the use of data to make informed decisions.
The integrated system (LabDisk, DDMS & Game) will be implemented in four sub-Saharan African countries, highly representative of malaria settings and vector control problems, to support informed decision-making about vector control and disease management. It will cover the urgent needs of an existing “market” and will provide solution to end users, to address a most important societal challenge in Africa, the control of malaria. The system has a vast expansion potential in other applications.
Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS

Address

N Plastira Str 100
70013 Heraklion

Greece

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 470 725

Participants (9)

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HAHN-SCHICKARD-GESELLSCHAFT FUER ANGEWANDTE FORSCHUNG E.v.

Germany

EU Contribution

€ 440 910,41

LIVERPOOL SCHOOL OF TROPICAL MEDICINE

United Kingdom

EU Contribution

€ 505 355

JIMMA UNIVERSITY

Ethiopia

EU Contribution

€ 264 598,75

MINISTRY OF HEALTH

Zambia

EU Contribution

€ 267 523,75

Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale

Cameroon

EU Contribution

€ 267 500

N.T. LABORATORY SRL

Italy

EU Contribution

€ 213 888,34

FAST TRACK DIAGNOSTICS LUXEMBOURG SARL

Luxembourg

EU Contribution

€ 295 000

SCHWEIZERISCHES TROPEN- UND PUBLIC HEALTH-INSTITUT

Switzerland

AGRICULTURAL UNIVERSITY OF ATHENS

Greece

EU Contribution

€ 42 500

Project information

Grant agreement ID: 688207

Status

Ongoing project

  • Start date

    1 February 2016

  • End date

    31 January 2020

Funded under:

H2020-EU.2.1.1.

  • Overall budget:

    € 3 167 376,25

  • EU contribution

    € 2 768 001,25

Coordinated by:

FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS

Greece