Periodic Reporting for period 3 - SENSE-Cog (Ears, Eyes and Mind: The ‘SENSE-Cog Project’ to improve mental well-being for elderly Europeans with sensory impairment)
Reporting period: 2019-01-01 to 2020-12-31
This WP is now complete. Using existing data from several large-scale aging cohorts from the EU and the USA, we completed in-depth epidemiological analyses to explore associations of vision/hearing loss with anxiety, depression, suicidal ideation, cognitive decline and risk of dementia, including a meta-analysis across datasets.
Work-Package 2: Assessment
To address the current lack of reliable assessment tools for people with cognitive and sensory impairments, we undertook a critical review of cognitive assessment tools for people with sensory impairment; a stakeholder needs’ analysis involving people with dementia (PwD), caregivers and health care professionals; development of a protocol to adapt a common cognitive tool (MOCA) and functional tool (DemPal) for people with hearing and vision impairment; and development and validation of an online tool (the E-checker) to detect cognition, hearing and vision problems.
Work-Package 3: Intervention
We iteratively developed and field tested a ‘sensory support intervention’ for evaluation in PwD with hearing and/or vision problems to improve their quality of life. This intervention is now being evaluated in a 5-nation trial that is nearly completion.
Work-Package 4: Valuation
We are studying the economic cost of the interaction among mental health and sensory impairment in existing EU databases. We have developed and field-tested health economics’ data collection tools which are embedded within the clinical trial of WP3 and model to analyse these data have been developed ready to implement when the data collection is complete.
Work-Package 5: Involvement
This WP is now complete. Involving PwD and their care partners is a crucial aspect of conducting meaningful research. To support, inform and guide the SENSE-Cog project and ensure that we are meeting the needs of PwD and their care partners, we have: established a network of ‘Research User Groups’ (RUGs) across the EU; trained the groups in research; set-up a public website and social media accounts; started evaluation of the effectiveness of our training programme; and hosted successful PPI consultation and dissemination events in several EU sites, including Manchester, Athens, Nice, and Nicosia.
Work-Package 2: We are nearly completion for data collection for validation of widely used cognitive test (the MOCA) adapted for people with sensory impairment We completed a critical review of online cognitive assessment tools and are mid-way through validation of our on-line screening tool (the SENSE-Cog E-checker) in five EU countries. This work will feed into an on-line Toolkit for professional and lay stakeholders.
Work-Package 3: We developed and field tested a new home-based psychosocial intervention to improve quality of life in people with dementia and sensory impairment, which is now being evaluated in a full randomised controlled trial in five countries and is nearly completion.
Work-Package 4: Econometric analyses from the SHARE meta-dataset identified that cognitive and sensory impairments are associated with higher use of health care services, even after controlling for other major health conditions.
Work-Package 5: We held public engagement events with >250 people, spreading the principles of ‘patient and public involvement’ (PPI) in the EU. We are evaluating methods to provide a gold standard for PPI in dementia. We have a publishable protocol training evaluation for our EU-wide Research User Groups (RUGS), contributing to the methodology of conduction PPI internationally in the dementia field
Work-Package 6: The WP6 team has successfully delivered the Steering Committee Meetings and the Annual General Meetings, held in October 2019 face-to-face in Dublin, Ireland and virtual in October 2020, and attended by all consortium partners.
Work-Package 7: We have undertaken Ethics’ Advisory Board reviews and gained approval for all work from our external ethics lead and submitted a detailed report to the European Commission for an ethics audit. Our report was favourably reviewed and no amendments were requested. Due to the COVID-19 pandemic, ongoing ethics’ amendments to WP2 and WP3 have been needed. These have been favourably reviewed by our EAB.