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Bioinformatics Services for Data-Driven Design of Cell Factories and Communities

Objective

Omics data is not leveraged effectively in the biotechnology industry due to lack of tools to rapidly access public and private data and to design cellular manipulations or interventions based on the data. With this project we aim to make a broad spectrum of omics data useful to the biotechnology industry covering application areas ranging from industrial biotechnology to human health. We will develop novel approaches for integrative model-based omics data analysis to enable 1) Identification of novel enzymes and pathways by mining metagenomic data, 2) Data-driven design of cell factories for the production of chemicals and proteins, and 3) Analysis and design of microbial communities relevant to human health, industrial biotechnology and agriculture. All research efforts will be integrated in an interactive web-based platform that will be available for the industrial and academic research and development communities, in particular enhancing the competitiveness of biotech SMEs by economizing resources and reducing time-to-market within their respective focus areas. The platform will be composed of standardized and interoperable components that service-oriented bioinformatics SMEs involved in the project can reuse in their own products. An important aspect of the platform will be implementation of different access levels to data and software tools allowing controlling access to proprietary data and analysis tools. Two end-user companies will be involved in practical testing of the platform built within the project using proprietary omics data generated at the companies.

Field of science

  • /engineering and technology/industrial biotechnology
  • /natural sciences/computer and information sciences/data science/data analysis

Call for proposal

H2020-LEIT-BIO-2015-1
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

DANMARKS TEKNISKE UNIVERSITET
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Denmark
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 776 110

Participants (10)

CHALMERS TEKNISKA HOEGSKOLA AB
Sweden
EU contribution
€ 861 412,50
Address
-
41296 Goeteborg
Activity type
Higher or Secondary Education Establishments
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 1 457 952,50
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Switzerland
EU contribution
€ 0
Address
Batiment Ce 3316 Station 1
1015 Lausanne
Activity type
Higher or Secondary Education Establishments
UNIVERSIDADE DO MINHO
Portugal
EU contribution
€ 341 691,25
Address
Largo Do Paco
4704 553 Braga
Activity type
Higher or Secondary Education Establishments
SILICOLIFE LDA
Portugal
EU contribution
€ 347 500
Address
Rua Do Canastreiro 15
4715 387 Braga
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
GENIALIS D.O.O
Slovenia
EU contribution
€ 536 875
Address
Koprska Ulica 72
1000 Ljubljana
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BIOBYTE SOLUTIONS GMBH
Germany
EU contribution
€ 251 250
Address
Bothestrasse 142
69126 Heidelberg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BIOSYNTIA APS
Denmark
EU contribution
€ 250 000
Address
Kogle Alle 6
2970 Horsholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DSM FOOD SPECIALTIES BV
Netherlands
EU contribution
€ 323 750
Address
Alexander Fleminglaan 1
2613 AX Delft
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSIDAD POLITECNICA DE MADRID
Spain
EU contribution
€ 104 095
Address
Calle Ramiro De Maeztu 7 Edificio Rectorado
28040 Madrid
Activity type
Higher or Secondary Education Establishments