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Bioinformatics Services for Data-Driven Design of Cell Factories and Communities

Bioinformatics Services for Data-Driven Design of Cell Factories and Communities

Objective

Omics data is not leveraged effectively in the biotechnology industry due to lack of tools to rapidly access public and private data and to design cellular manipulations or interventions based on the data. With this project we aim to make a broad spectrum of omics data useful to the biotechnology industry covering application areas ranging from industrial biotechnology to human health. We will develop novel approaches for integrative model-based omics data analysis to enable 1) Identification of novel enzymes and pathways by mining metagenomic data, 2) Data-driven design of cell factories for the production of chemicals and proteins, and 3) Analysis and design of microbial communities relevant to human health, industrial biotechnology and agriculture. All research efforts will be integrated in an interactive web-based platform that will be available for the industrial and academic research and development communities, in particular enhancing the competitiveness of biotech SMEs by economizing resources and reducing time-to-market within their respective focus areas. The platform will be composed of standardized and interoperable components that service-oriented bioinformatics SMEs involved in the project can reuse in their own products. An important aspect of the platform will be implementation of different access levels to data and software tools allowing controlling access to proprietary data and analysis tools. Two end-user companies will be involved in practical testing of the platform built within the project using proprietary omics data generated at the companies.

Coordinator

DANMARKS TEKNISKE UNIVERSITET

Address

Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby

Denmark

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 1 776 110

Participants (10)

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CHALMERS TEKNISKA HOEGSKOLA AB

Sweden

EU Contribution

€ 861 412,50

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Germany

EU Contribution

€ 1 457 952,50

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

Switzerland

UNIVERSIDADE DO MINHO

Portugal

EU Contribution

€ 341 691,25

SILICOLIFE LDA

Portugal

EU Contribution

€ 347 500

GENIALIS D.O.O

Slovenia

EU Contribution

€ 536 875

BIOBYTE SOLUTIONS GMBH

Germany

EU Contribution

€ 251 250

BIOSYNTIA APS

Denmark

EU Contribution

€ 250 000

DSM FOOD SPECIALTIES BV

Netherlands

EU Contribution

€ 323 750

UNIVERSIDAD POLITECNICA DE MADRID

Spain

EU Contribution

€ 104 095

Project information

Grant agreement ID: 686070

Status

Ongoing project

  • Start date

    1 March 2016

  • End date

    29 February 2020

Funded under:

H2020-EU.2.1.4.

  • Overall budget:

    € 7 091 021,25

  • EU contribution

    € 6 250 636,25

Coordinated by:

DANMARKS TEKNISKE UNIVERSITET

Denmark