Periodic Reporting for period 1 - Edible Neuroprosthetics (Development of fully dissolvable devices and application as implanted neuroprostheses)
Reporting period: 2016-04-01 to 2018-03-31
 Zrenner, E. Sci Transl Med (2013).
 Borton, D. et al. Sci Transl Med (2013).
 Lanzani, G. Nature Materials (2014).
 Hwang, S.-W. et al. Science (2012).
 Hwang, S.-W. et al. Nano letters (2015).
Full absorbability of the device is currently under investigation. A series of neural probes were fabricated and implanted in mice brains (visual cortex area) to assess the materials durability in-vivo. Several time-points (1, 3, 6, 9 and 12 months) have been established for the implant analysis in order to have a better comprehension of the degradation process within the biological environment and the response of the biological environment itself to the insertion of the selected materials.
Results on the advancements of this project have been presented as poster and oral contributions at the following international conferences:
- International Conference on Organic Electronics 2017, Saint Petersbourg (RUS) 4th-8th June 2017 (poster)
- Materials Research Society Fall Meeting 2017, Boston (MA, USA) November 26th-December 1st 2017 (oral)
- Gordon Research Conference Neuroelectronic Interfaces, Galveston (TX, USA) 25th-30th March 2018 (poster)
The scientific advancement provided by the project will have a major impact on the entire Neuroprosthetic field, by paving the way for a new set of implants characterized by the transient presence in the body. This will have a major impact in term of tolerability, avoiding the need for surgical retrieval, and greatly reducing their invasiveness. Overall, this concept will make the field of Neuroprosthetics much more attractive and helpful for medical application.