Skip to main content

European Lead Factory

Objective

The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provide an industry-like small molecule discovery platform to public investigators. It builds on a unique, comprehensive, high-quality compound collection contributed by EFPIA Pparticipants, i.e. the Pharma Consortium Compound Collection totaling over about 300.000 compounds. Screening of these previously safeguarded corporate compound libraries against competitor’s targets and targets from public sources may result in otherwise inaccessible valuable lead structures that could ultimately result in the development of novel treatment options for patients. Academic Participantsa or other eligible bodies (and Contributing Third Parties) will be invited to submit proposals for screening of innovative targets and to suggest the design of new and diverse chemical libraries utilizing novel concepts and strategies. The latter will fuel the generation of a Public Compound Collection that will combine with the Pharma ConsortiumEFPIA Compound Collection to generate the Joint European Compound CollectionLibrary. These public sector contributions will not only provide a constant flow of innovation, but also generate opportunities for future partnerships amongst public Public Participants and private contributors EFPIA Participants on scientific and commercial grounds. EUC2LID’s overarching goal is value creation by screening the Joint European Compound Collection Library against in pPublic and private EFPIA Ttarget Programmes. Based on the successful delivery on its objectives during the IMI funding period, the generation of the high quality Public Compound Collection provides a tangible asset allowing the transition of the European Lead Factory into a novel sustainable business model, facilitating future public-private alliances based on pre-competitive, community-based efforts in early drug research.

Call for proposal

IMI-JU-05-2012
See other projects for this call

Coordinator

BAYER AKTIENGESELLSCHAFT
Address
Kaiser-wilhelm-allee 1
51373 Leverkusen
Germany
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Principal investigator
Stefan Jaroch (Dr.)
Administrative Contact
Petra Freitag (Ms)

Participants (32)

UNIVERSITEIT LEIDEN
Netherlands
EU contribution
€ 828 076
Address
Rapenburg 70
2311 EZ Leiden
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Bart van der Hoorn (Mr.)
BioCity Scotland Ltd

Participation ended

United Kingdom
EU contribution
€ 2 198 018
Address
Bo’ness Road
ML1 5UH Newhouse
Administrative Contact
Glenn Crocker (Dr)
PIVOT PARK SCREENING CENTRE BV
Netherlands
EU contribution
€ 16 382 800
Address
Kloosterstraat 9
5349 AB Oss
Activity type
Research Organisations
Administrative Contact
Mirjam Mol-Arts (Mrs.)
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 964 585
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Gill Wells (Ms)
UNIVERSITY OF DUNDEE
United Kingdom
EU contribution
€ 10 321 075
Address
Nethergate
DD1 4HN Dundee
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Bridget Glaysher (Ms)
TAROS CHEMICALS GMBH & CO KG
Germany
EU contribution
€ 7 444 995
Address
Emil-figge-str. 76A
44227 Dortmund
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Alexander Piechot (Dr.)
MERCACHEM BV
Netherlands
EU contribution
€ 5 254 347
Address
Kerkenbos 1013
6546BB Nijmegen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ted Roverts (MBA)
LEAD DISCOVERY CENTER GMBH
Germany
EU contribution
€ 474 698
Address
Otto Hahn Strasse 15
44227 Dortmund
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Michael Hamacher (Dr.)
EDELRIS SAS
France
EU contribution
€ 5 097 700
Address
Avenue Rockefeller 60
69008 Lyon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
CATHERINE VIDAL (Dr)
SYNCOM BV
Netherlands
EU contribution
€ 4 980 753
Address
Kadijk 3
9747 AT Groningen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ton Vries (PhD)
SYGNATURE DISCOVERY LIMITED
United Kingdom
EU contribution
€ 5 114 237
Address
Pennyfoot Street Biocity
NG1 1GF Nottingham
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Victoria Tabiner (Mrs)
GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG

Participation ended

Germany
EU contribution
€ 451 477
Address
Oskar Von Miller Ring 29
80333 Muenchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Birgit Fuchs (Mrs.)
STICHTING LYGATURE
Netherlands
EU contribution
€ 2 778 883
Address
Jaarbeursplein 6
3521 AL Utrecht
Activity type
Other
Administrative Contact
Dionysius Willem Cornelis Groot (Mr.)
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
EU contribution
€ 1 209 624
Address
University Park
NG7 2RD Nottingham
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Cartledge (Mr)
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS

Participation ended

Netherlands
EU contribution
€ 401 449
Address
Plesmanlaan 121
1066 CX Amsterdam
Activity type
Research Organisations
Administrative Contact
Henri Van Luenen (Dr.)
UNIVERSITAET DUISBURG-ESSEN
Germany
EU contribution
€ 779 096
Address
Universitatsstrasse 2
45141 Essen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kirsten Gercek (Ms)
STICHTING VU
Netherlands
EU contribution
€ 820 434
Address
De Boelelaan 1105
1081 HV Amsterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Bart van Leijen (Drs.)
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
EU contribution
€ 2 053 986
Address
Hofgartenstrasse 8
80539 Munchen
Activity type
Research Organisations
Administrative Contact
Kamal Kumar (Mr.)
STICHTING RADBOUD UNIVERSITEIT
Netherlands
EU contribution
€ 800 748
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kim Fransen (Ms.)
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 984 780
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Pernille Wigh (Ms.)
UNIVERSITY OF LEEDS
United Kingdom
EU contribution
€ 1 532 940
Address
Woodhouse Lane
LS2 9JT Leeds
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Martin Hamilton (Mr)
RIJKSUNIVERSITEIT GRONINGEN
Netherlands
EU contribution
€ 749 820
Address
Broerstraat 5
9712CP Groningen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Dick Veldhuis (Dr)
JANSSEN PHARMACEUTICA NV
Belgium
Address
Turnhoutseweg 30
2340 Beerse
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Karien Peeters (Ms.)
Merck KGaA
Germany
Address
Frankfurter Strasse 250
64293 Darmstadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ninog Péresse (Mrs.)
ASTRAZENECA AB
Sweden
Address
Vastra Maelarhamnen
151 85 Sodertaelje
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Eva Lindgren (Senior Director)
SANOFI-AVENTIS DEUTSCHLAND GMBH
Germany
Address
Bruningstrasse 50
65929 Frankfurt Am Main
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Thorsten Strube (Dr.)
UCB PHARMA SA
Belgium
Address
Allee De La Recherche 60
1070 Bruxelles
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Simon DRESSE (Mr)
H. LUNDBECK AS
Denmark
Address
Ottiliavej 7-9
2500 Valby
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ejner Knud Moltzen (MS)
ChemAxon Kutató-Fejlesztő Korlátolt Felelősségű Társaság
Hungary
EU contribution
€ 370 200
Address
Záhony Utca
1031 Budapest
Administrative Contact
István Bágyi (Dr.)
BIOASCENT DISCOVERY LIMITED
United Kingdom
EU contribution
€ 7 354 592
Address
Bo Ness Road
ML1 5UH Newhouse
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Simon MacKenzie (Dr)
ARTTIC
France
EU contribution
€ 254 123
Address
Rue Du Dessous Des Berges 58A
75013 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Martin Dietz (Dr)
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
EU contribution
€ 395 721
Address
Albinusdreef 2
2333 ZA Leiden
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Michael van Harmelen (-)