Novel diagnostic and therapeutic approach to inflammatory bowel disease based on functional characterization of patients: the CrUCCial index

Publications

P027 Epithelial cells of patients with ulcerative colitis do not show an increased sensitivity after microbiota stimulation compared to non-IBD controls

Auteurs: K Arnauts, C Lapierre, B Verstockt, S Verstockt, P Sudhakar, S Vermeire, C Verfaillie, J Sabino, M Ferrante
Publié dans: Journal of Crohn's and Colitis, 2021
Éditeur: Oxford University Press
DOI: 10.1093/ecco-jcc/jjab076.156

DOP22 Integrative -omic analysis reveals microbiota mediated molecular mechanisms influencing host mucosal gene expression in Crohn’s Disease

Auteurs: P Sudhakar, T Andrighetti, S Verstockt, C Caenepeel, M Ferrante, J Sabino, B Verstockt, S Vermeire
Publié dans: Journal of Crohn's and Colitis, 2021
Éditeur: Oxford University Press
DOI: 10.1093/ecco-jcc/jjab073.061

Mo1127: BLOOD IMMUNE CELL DRIVED TRANSCRIPTIONAL SIGNATURES ASSOCIATED WITH DISEASE LOCATION IN IBD

Auteurs: Padhmanand Sudhakar, Bram Verstockt, Jonathan Cremer, Sare Verstockt, João Sabino, Marc Ferrante, Séverine Vermeire
Publié dans: Gastroenterology, Numéro 18739946, 2022, ISSN 1873-9946
Éditeur: Elsevier
DOI: 10.1016/s0016-5085(22)61660-3

P004 Microbiota, not host origin drives ex vivo epithelial response in ulcerative colitis patients and non-IBD controls

Auteurs: K Arnauts, P Sudhakar, S Verstockt, C Lapierre, S Potche, C Caenepeel, B Verstockt, J Raes, S Vermeire, J Sabino, C Verfaillie, M Ferrante
Publié dans: Journal of Crohn's and Colitis, 2022
Éditeur: Oxford University Press
DOI: 10.1093/ecco-jcc/jjab232.133

Mo1513: THE DYNAMIC OF THE MOLECULAR-BASED CLASSIFICATION OF CROHN’S DISEASE

Auteurs: Nasim Sadat Seyed Tabib, Sare Verstockt, Bram Verstockt, João Sabino, Marc Ferrante, Séverine Vermeire
Publié dans: GASTROENTEROLOGY, 2022, Page(s) 18739946
Éditeur: Elsevier
DOI: 10.1016/s0016-5085(22)61885-7

DOP08 Transcriptional signatures of blood derived immune cells associated with disease location-based heterogeneity in IBD

Auteurs: P Sudhakar, B Verstockt, J Cremer, S Verstockt, J Sabino, M Ferrante, S Vermeire
Publié dans: Journal of Crohn's and Colitis, 2022
Éditeur: Oxford University Press
DOI: 10.1093/ecco-jcc/jjab232.047

Tu1862 Profiling of the Fecal Microbiota and Metabolome in Patients with Inflammatory Bowel Disease and their Unaffected Relatives

Auteurs: Maaike Vancamelbeke, João Sabino, Lise Deroover, Greet Vandermeulen, Anja Luypaerts, Marc Ferrante, Gwen Falony, Sara Vieira-Silva, Kristin Verbeke, Jeroen Raes, Isabelle Cleynen, Severine Vermeire
Publié dans: Gastroenterology, Numéro 152/5, 2017, Page(s) S991, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

Tu1770 Genetic Defects in ER Stress and Autophagy Translate Into Increased Functional ER Stress Levels in Patients with Inflammatory Bowel Disease

Auteurs: Wiebe Vanhove, Kris Nys, Ingrid Arijs, Isabelle Cleynen, Magali de Bruyn, Hannelie Korf, Marc Ferrante, Gert A. Van Assche, Severine Vermeire
Publié dans: Gastroenterology, Numéro 152/5, 2017, Page(s) S963-S964, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

Tu1856: Impact of Ileocecal Resection in Crohn's Disease Patients on Fecal Microbiota

Auteurs: Kathleen Machiels, Victoria Pascal, João Sabino, Alba Santiago, David Campos, Albert Wolthuis, Anthony de Buck van Overstraeten, Andre D'Hoore, Gert A. Van Assche, Marc Ferrante, Paul Rutgeerts, Chaysavanh Manichanh, Severine Vermeire
Publié dans: Gastroenterology, Numéro 152/5, 2017, Page(s) S989-S990, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

P084 Ileal gene expression changes are associated with colonic disease activity in patients with ulcerative colitis

Auteurs: M Vancamelbeke, S Verstockt, M Ferrante, G Van Assche, S Vermeire, I Cleynen
Publié dans: Journal of Crohn's and Colitis, Numéro 12/supplement_1, 2018, Page(s) S134-S136, ISSN 1873-9946
Éditeur: Elsevier Science

P117 Serum proteomic analysis characterises newly diagnosed Crohn’s disease and ulcerative colitis depending on the age at diagnosis

Auteurs: S Verstockt, E Glorieus, M De Decker, B Verstockt, N Ardeshir Davani, V Ballet, G Van Assche, P Hindryckx, M Ferrante, D Laukens, F Mana, M De Vos, S Vermeire, I Cleynen
Publié dans: Journal of Crohn's and Colitis, Numéro 12/supplement_1, 2018, Page(s) S151-S152, ISSN 1873-9946
Éditeur: Elsevier Science

P854 Quantitative microbiome profiling changes the described dysbiotic state in inflammatory bowel disease

Auteurs: C Caenepeel, S Vieira-Silva, J Sabino, K Machiels, G Falony, M Ferrante, G Van Assche, J Raes, S Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 12/supplement_1, 2018, Page(s) S548-S549, ISSN 1873-9946
Éditeur: Elsevier Science

OP003 Temporal changes in immune pathways with consecutive biological therapies as measured by serum proteomics

Auteurs: M de Bruyn, V Ballet, S Verstockt, B Verstockt, G Van Assche, M Ferrante, K Machiels, S Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 12/supplement_1, 2018, Page(s) S003-S003, ISSN 1873-9946
Éditeur: Elsevier Science

P104 Gene expression profiles in inflamed colonic biopsies from newly diagnosed Crohn’s disease and ulcerative colitis patients differ depending on the age at diagnosis

Auteurs: S Verstockt, B Verstockt, J Van Bouwel, W Meert, A Cortes Calabuig, V Brys, V Ballet, E Glorieus, M De Decker, G Van Assche, P Hindryckx, M Ferrante, D Laukens, F Mana, M De Vos, S Vermeire, I Cleynen
Publié dans: Journal of Crohn's and Colitis, Numéro 12/supplement_1, 2018, Page(s) S146-S146, ISSN 1873-9946
Éditeur: Elsevier Science

Tu1857: Mucosal Recolonization after Ileocecal Resection Differs in Crohn's Disease Patients Developing Postoperative Recurrence

Auteurs: Kathleen Machiels, Marta Pozuelo del Río, João Sabino, Alba Santiago, David Campos, Albert Wolthuis, Anthony de Buck van Overstraeten, Andre D'Hoore, Gert A. Van Assche, Marc Ferrante, Paul Rutgeerts, Gert De Hertogh, Severine Vermeire, Chaysavanh Manichanh
Publié dans: Gastroenterology, Numéro 152/5, 2017, Page(s) S990, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

P042 Decreased leukocyte trafficking may contribute to vedolizumab refractory disease after anti-TNF exposure in patients with ulcerative colitis

Auteurs: B Verstockt, S Verstockt, M de Bruyn, K Machiels, H Blevi, V Ballet, G Van Assche, S Vermeire, M Ferrante
Publié dans: Journal of Crohn's and Colitis, Numéro 12/supplement_1, 2018, Page(s) S113-S113, ISSN 1873-9946
Éditeur: Elsevier Science

P052 Protein biomarkers identify subclinical inflammation patterns in first-degree relatives of patients with inflammatory bowel disease

Auteurs: M Vancamelbeke, V Ballet, N Ardeshir Davani, G Van Assche, M Ferrante, I Cleynen, S Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 12/supplement_1, 2018, Page(s) S118-S119, ISSN 1873-9946
Éditeur: Elsevier Science

P010 Serum proteomic profiling in Crohn’s disease patients undergoing ileocolonic resection reveals discriminative inflammatory markers for endoscopic recurrence

Auteurs: K Machiels, M de Bruyn, S Verstockt, B Verstockt, G Van Assche, A Wolthuis, A d'Hoore, M Ferrante, S Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 12/supplement_1, 2018, Page(s) S096-S097, ISSN 1873-9946
Éditeur: Elsevier Science

P035 Serum markers predict outcome to ustekinumab in patients with refractory Crohn’s disease and provide insides in the mechanism of action

Auteurs: B Verstockt, S Vermeire, S Verstockt, B Creyns, N Ardeshir Davani, C Breynaert, G Van Assche, G Van Assche, M Ferrante
Publié dans: Journal of Crohn's and Colitis, Numéro 12/supplement_1, 2018, Page(s) S110-S110, ISSN 1873-9946
Éditeur: Elsevier Science

Tu1799 - Serum Proteomic Profiling Reveals Changes in Inflammatory Profiles with Consecutive Biological Therapies in Patients with Inflammatory Bowel Disease

Auteurs: Magali de Bruyn, Vera Ballet, Sare Verstockt, Bram Verstockt, Gert A. Van Assche, Marc Ferrante, Kathleen Machiels, Severine Vermeire
Publié dans: Gastroenterology, Numéro 154/6, 2018, Page(s) S-1023, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

P774 Metagenomics and metabolomics of patients with inflammatory bowel disease and their unaffected relatives

Auteurs: M. Vancamelbeke, J. Sabino, L. Deroover, G. Vandermeulen, A. Luypaerts, M. Ferrante, G. Falony, S. Vieira-Silva, K. Verbeke, J. Raes, I. Cleynen, S. Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 11/suppl_1, 2017, Page(s) S476-S477, ISSN 1873-9946
Éditeur: Elsevier Science

Sa1784 - Unaffected First-Degree Relatives of Patients with Inflammatory Bowel Disease have Altered Profiles of Inflammation-Related Proteins

Auteurs: Maaike Vancamelbeke, Vera Ballet, Nooshin Ardeshir Davani, Gert A. Van Assche, Marc Ferrante, Isabelle Cleynen, Severine Vermeire
Publié dans: Gastroenterology, Numéro 154/6, 2018, Page(s) S-393, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

Tu1808 - Colonic Inflammation Determines Ileal Gene Expression Changes in Ulcerative Colitis

Auteurs: Maaike Vancamelbeke, Sare Verstockt, Marc Ferrante, Gert A. Van Assche, Severine Vermeire, Isabelle Cleynen
Publié dans: Gastroenterology, Numéro 154/6, 2018, Page(s) S-1025-S-1026, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

Su1794 - Discrimination of Endoscopic Postoperative Recurrence in Patients with Crohn's Disease using Serological Inflammatory Markers

Auteurs: Kathleen Machiels, Magali de Bruyn, Sare Verstockt, Bram Verstockt, Gert A. Van Assche, Albert Wolthuis, Andre D'Hoore, Marc Ferrante, Severine Vermeire
Publié dans: Gastroenterology, Numéro 154/6, 2018, Page(s) S-586-S-587, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

OP038 Impact of ileocecal resection in Crohn's disease patients on mucosal microbiota

Auteurs: K. Machiels, M. Pozuelo del Río, J. Sabino, A. Santiago, D. Campos, A. Wolthuis, A. De Buck van Overstraeten, A. D'Hoore, G. Van Assche, M. Ferrante, P. Rutgeerts, G. De Hertogh, S. Vermeire, C. Manichanh
Publié dans: Journal of Crohn's and Colitis, Numéro 11/suppl_1, 2017, Page(s) S24-S25, ISSN 1873-9946
Éditeur: Elsevier Science

DOP044 Relationship between microbiota and development of early postoperative Crohn's disease recurrence

Auteurs: K. Machiels, V. Pascal, J. Sabino, A. Santiago, D. Campos, A. Wolthuis, A. De Buck van Overstraeten, A. D'Hoore, G. Van Assche, M. Ferrante, P. Rutgeerts, C. Manichanh, S. Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 11/suppl_1, 2017, Page(s) S53-S53, ISSN 1873-9946
Éditeur: Elsevier Science

OP30 Serum proteomic profiling predicts and diagnoses pouchitis in ulcerative colitis patients undergoing ileal pouch-anal anastomosis

Auteurs: K Machiels, M Ferrante, N Davani, A Wolthuis, A D’Hoore, S Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 13/Supplement_1, 2019, Page(s) S022-S023, ISSN 1873-9946
Éditeur: Elsevier Science

DOP70 An integrated multi-omics biomarker predicting endoscopic response in ustekinumab treated patients with Crohn's disease

Auteurs: B Verstockt, P Sudahakar, B Creyns, S Verstockt, J Cremer, W-J Wollants, S Organe, T Korcsmaros, M Madgwick, G Van Assche, C Breynaert, S Vermeire, M Ferrante
Publié dans: Journal of Crohn's and Colitis, Numéro 13/Supplement_1, 2019, Page(s) S072-S073, ISSN 1873-9946
Éditeur: Elsevier Science

DOP38 A vedolizumab specific four-gene colonic signature accurately predicting future endoscopic remission in patients with inflammatory bowel disease

Auteurs: B Verstockt, S Verstockt, P Sudahakar, J Dehairs, H Blevi, G Van Assche, S Vermeire, M Ferrante
Publié dans: Journal of Crohn's and Colitis, Numéro 13/Supplement_1, 2019, Page(s) S048-S048, ISSN 1873-9946
Éditeur: Elsevier Science

P385 TREM1, the first anti-TNF specific biomarker guiding therapeutic decision

Auteurs: B Verstockt, S Verstockt, J Dehairs, V Ballet, H Blevi, W-J Wollants, C Breynaert, G Van Assche, S Vermeire, M Ferrante
Publié dans: Journal of Crohn's and Colitis, Numéro 13/Supplement_1, 2019, Page(s) S300-S300, ISSN 1873-9946
Éditeur: Elsevier Science

P001 Multi-omic data integration assisted identification of molecular features contributing to disease heterogeneity in Crohn's disease

Auteurs: P Sudhakar, B Verstockt, B Creyns, J Cremer, G van Assche, T Korcsmaros, M Ferrante, S Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 13/Supplement_1, 2019, Page(s) S085-S086, ISSN 1873-9946
Éditeur: Elsevier Science

Sa1781 - Serological Markers Define Newly Diagnosed Crohn's Disease and Ulcerative Colitis Based on the age at Diagnosis

Auteurs: Sare Verstockt, Elien Glorieus, Muriel De Decker, Bram Verstockt, Nooshin Ardeshir Davani, Vera Ballet, Gert A. Van Assche, Pieter Hindryckx, Marc Ferrante, Debby Laukens, Fazia Mana, Martine De Vos, Severine Vermeire, Isabelle Cleynen
Publié dans: Gastroenterology, Numéro 154/6, 2018, Page(s) S-392, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

OP10 Systems genomics of ulcerative colitis: combining GWAS and signalling networks for patient stratification and individualised drug targeting in ulcerative colitis

Auteurs: J Brooks, D Modos, P Sudhakar, D Fazekas, A Zoufir, A Watson, M Tremelling, B Verstockt, S Vermeire, A Bender, S Carding, T Korcsmaros
Publié dans: Journal of Crohn's and Colitis, Numéro 13/Supplement_1, 2019, Page(s) S006-S007, ISSN 1873-9946
Éditeur: Elsevier Science

P821 Distinct and common gene expression profiles between inflamed ileum and colon of newly diagnosed CD patients

Auteurs: S Verstockt, F Ver Donck, B Verstockt, M Vancamelbeke, M De Decker, E Glorieus, V Ballet, G Van Assche, D Laukens, M Ferrante, F Mana, M De Vos, S Vermeire, I Cleynen
Publié dans: Journal of Crohn's and Colitis, Numéro 13/Supplement_1, 2019, Page(s) S533-S533, ISSN 1873-9946
Éditeur: Elsevier Science

Tu1810 - Transcriptomic Profile of Inflamed Colonic Biopsies from Newly Diagnosed Crohn's Disease and Ulcerative Colitis Patients Depend on the age at Diagnosis

Auteurs: Sare Verstockt, Bram Verstockt, Jens Van Bouwel, Wim Meert, Alvaro Cortés Calabuig, Vanessa Brys, Vera Ballet, Elien Glorieus, Muriel De Decker, Gert A. Van Assche, Pieter Hindryckx, Marc Ferrante, Debby Laukens, Fazia Mana, Martine De Vos, Severine Vermeire, Isabelle Cleynen
Publié dans: Gastroenterology, Numéro 154/6, 2018, Page(s) S-1026, ISSN 0016-5085
Éditeur: W. B. Saunders Co., Ltd.

P827 Up-regulation of IL17-related pathways in affected colon from ulcerative colitis compared with Crohn’s disease

Auteurs: S Verstockt, F Ver Donck, B Verstockt, E Glorieus, M De Decker, V Ballet, G Van Assche, D Laukens, M Ferrante, F Mana, M De Vos, S Vermeire, I Cleynen
Publié dans: Journal of Crohn's and Colitis, Numéro 13/Supplement_1, 2019, Page(s) S537-S538, ISSN 1873-9946
Éditeur: Elsevier Science

P836 The predictive role of gut microbiota in treatment response to vedolizumab and ustekinumab in inflammatory bowel disease

Auteurs: C Caenepeel, S Vieira-Silva, B Verstockt, M Ferrante, J Raes, S Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 13/Supplement_1, 2019, Page(s) S542-S542, ISSN 1873-9946
Éditeur: Elsevier Science

OP30 The interplay of microbiome dysbiosis and immune system deregulation in patients with Crohn’s disease

Auteurs: N S Seyed Tabib, C Caenepeel, K Machiels, S Verstockt, B Verstockt, N Ardeshir Davani, J Sabino, M Ferrante, S Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 14/Supplement_1, 2020, Page(s) S028–S030
Éditeur: Elsevier Science

Understanding the Molecular Drivers of Disease Heterogeneity in Crohn’s Disease Using Multi-omic Data Integration and Network Analysis

Auteurs: Padhmanand Sudhakar, Bram Verstockt, Jonathan Cremer, Sare Verstockt, João Sabino, Marc Ferrante, Séverine Vermeire
Publié dans: Inflammatory Bowel Diseases, 2020, ISSN 1078-0998
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1093/ibd/izaa281

Expression Levels of 4 Genes in Colon Tissue Might Be Used to Predict Which Patients Will Enter Endoscopic Remission After Vedolizumab Therapy for Inflammatory Bowel Diseases

Auteurs: Bram Verstockt, Sare Verstockt, Marisol Veny, Jonas Dehairs, Kaline Arnauts, Gert Van Assche, Gert De Hertogh, Séverine Vermeire, Azucena Salas, Marc Ferrante
Publié dans: Clinical Gastroenterology and Hepatology, Numéro 18/5, 2020, Page(s) 1142-1151.e10, ISSN 1542-3565
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.cgh.2019.08.030

MicrobioLink: An Integrated Computational Pipeline to Infer Functional Effects of Microbiome–Host Interactions

Auteurs: Tahila Andrighetti, Balazs Bohar, Ney Lemke, Padhmanand Sudhakar, Tamas Korcsmaros
Publié dans: Cells, Numéro 20734409, 2020, ISSN 2073-4409
Éditeur: MDPI AG
DOI: 10.3390/cells9051278

Big data in IBD: big progress for clinical practice

Auteurs: Nasim Sadat Seyed Tabib, Matthew Madgwick, Padhmanand Sudhakar, Bram Verstockt, Tamas Korcsmaros, Séverine Vermeire
Publié dans: Gut, Numéro 69/8, 2020, Page(s) 1520-1532, ISSN 0017-5749
Éditeur: BMJ Publishing Group
DOI: 10.1136/gutjnl-2019-320065

Computational Biology and Machine Learning Approaches to Understand Mechanistic Microbiome-Host Interactions

Auteurs: Sudhakar P, Machiels K, Verstockt B, Korcsmaros T, Vermeire S
Publié dans: Frontiers in Microbiology, Numéro 1664302X, 2021, ISSN 1664-302X
Éditeur: Frontiers Media
DOI: 10.3389/fmicb.2021.618856

Integrated analysis of microbe-host interactions in Crohn’s disease reveals potential mechanisms of microbial proteins on host gene expression

Auteurs: Padhmanand Sudhakar, Tahila Andrighetti, Sare Verstockt, Clara Caenepeel, Marc Ferrante, João Sabino, Bram Verstockt, Severine Vermeire
Publié dans: iScience, 2022, ISSN 2589-0042
Éditeur: Elsevier
DOI: 10.1016/j.isci.2022.103963

Microbiota, not host origin drives ex vivo intestinal epithelial responses

Auteurs: Kaline Arnauts, Padhmanand Sudhakar, Sare Verstockt, Cynthia Lapierre, Selina Potche, Clara Caenepeel, Bram Verstockt, Jeroen Raes, Séverine Vermeire, João Sabino, Catherine Verfaillie, Marc Ferrante
Publié dans: Gut Microbes, Numéro 19490976, 2022, ISSN 1949-0976
Éditeur: Landes Bioscience
DOI: 10.1080/19490976.2022.2089003

Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease

Auteurs: Wiebe Vanhove, Kris Nys, Ingrid Arijs, Isabelle Cleynen, Manuel Noben, Sebastiaan De Schepper, Gert Van Assche, Marc Ferrante, Séverine Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 12/2, 2017, Page(s) 178-187, ISSN 1873-9946
Éditeur: Elsevier Science
DOI: 10.1093/ecco-jcc/jjx122

Genetic and Transcriptomic Bases of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease

Auteurs: Maaike Vancamelbeke, Tim Vanuytsel, Ricard Farré, Sare Verstockt, Marc Ferrante, Gert Van Assche, Paul Rutgeerts, Frans Schuit, Séverine Vermeire, Ingrid Arijs, Isabelle Cleynen
Publié dans: Inflammatory Bowel Diseases, Numéro 23/10, 2017, Page(s) 1718-1729, ISSN 1078-0998
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/MIB.0000000000001246

Human intestinal epithelium in a dish: Current models for research into gastrointestinal pathophysiology

Auteurs: Manuel Noben, Wiebe Vanhove, Kaline Arnauts, Anabela Santo Ramalho, Gert Van Assche, Séverine Vermeire, Catherine Verfaillie, Marc Ferrante
Publié dans: United European Gastroenterology Journal, Numéro 5/8, 2017, Page(s) 1073-1081, ISSN 2050-6406
Éditeur: Elsevier
DOI: 10.1177/2050640617722903

The intestinal barrier: a fundamental role in health and disease

Auteurs: Maaike Vancamelbeke, Séverine Vermeire
Publié dans: Expert Review of Gastroenterology & Hepatology, Numéro 11/9, 2017, Page(s) 821-834, ISSN 1747-4124
Éditeur: Future Drugs Ltd.
DOI: 10.1080/17474124.2017.1343143

Butyrate does not protect against inflammation-induced loss of epithelial barrier function and cytokine production in primary cell monolayers from patients with ulcerative colitis

Auteurs: Maaike Vancamelbeke, Thessa Laeremans, Wiebe Vanhove, Kaline Arnauts, Anabela Santo Ramalho, Ricard Farré, Isabelle Cleynen, Marc Ferrante, Séverine Vermeire
Publié dans: Journal of Crohn's and Colitis, 2019, ISSN 1873-9946
Éditeur: Elsevier Science
DOI: 10.1093/ecco-jcc/jjz064

Low TREM1 expression in whole blood predicts anti-TNF response in inflammatory bowel disease

Auteurs: Bram Verstockt, Sare Verstockt, Jonas Dehairs, Vera Ballet, Helene Blevi, Willem-Jan Wollants, Christine Breynaert, Gert Van Assche, Séverine Vermeire, Marc Ferrante
Publié dans: EBioMedicine, Numéro 40, 2019, Page(s) 733-742, ISSN 2352-3964
Éditeur: Elsevier BV
DOI: 10.1016/j.ebiom.2019.01.027

Mucosal IL13RA2 expression predicts nonresponse to anti-TNF therapy in Crohn's disease

Auteurs: Bram Verstockt, Sare Verstockt, Brecht Creyns, Sophie Tops, Gert Van Assche, Ann Gils, Jan L. Ceuppens, Séverine Vermeire, Marc Ferrante, Christine Breynaert
Publié dans: Alimentary Pharmacology & Therapeutics, Numéro 49/5, 2019, Page(s) 572-581, ISSN 0269-2813
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/apt.15126

A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis

Auteurs: Johanne Brooks-Warburton, Dezso Modos, Padhmanand Sudhakar, Matthew Madgwick, John P. Thomas, Balazs Bohar, David Fazekas, Azedine Zoufir, Orsolya Kapuy, Mate Szalay-Beko, Bram Verstockt, Lindsay J. Hall, Alastair Watson, Mark Tremelling, Miles Parkes, Severine Vermeire, Andreas Bender, Simon R. Carding & Tamas Korcsmaros
Publié dans: nature communications, Numéro 20411723, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-29998-8

Tailoring Multi-omics to Inflammatory Bowel Diseases: All for One and One for All

Auteurs: Padhmanand Sudhakar; Dahham Alsoud; Judith Wellens; Sare Verstockt; Kaline Arnauts; Bram Verstockt; Severine Vermeire
Publié dans: Journal of Crohn's and Colitis, Numéro 18739946, 2022, ISSN 1873-9946
Éditeur: Elsevier Science
DOI: 10.1093/ecco-jcc/jjac027

Distinct transcriptional signatures in purified circulating immune cells drive heterogeneity in disease location in IBD

Auteurs: Verstockt B, Cremer J, Verstockt S, Sabino J, Ferrante M, Vermeire S, Sudhakar P
Publié dans: BMJ Open Gastroenterology, Numéro 20544774, 2022, ISSN 2054-4774
Éditeur: BMJ Publishing Group
DOI: 10.1136/bmjgast-2022-001003

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