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Improving the flow in the pipeline of the next generation of marine biodiscovery scientists

Improving the flow in the pipeline of the next generation of marine biodiscovery scientists

Objective

MarPipe is a consortium of 11 partners (IBP-CNR, SZN, UiT, UNIABDN, GEOMAR, KULeuven, UCC, eCOAST, MEDINA, MicroDish, Italbiotec) based in 8 countries (I, N, UK, D, B, IRL, E, NL), including 3 from the non-academic sector. We will train 11 ESRs in marine drug-discovery, providing these researchers with unique skills toward becoming world leaders in this research field and to advance their careers in academia or industry. MarPipe PhDs will be trained in a programme including training-by-research, joint courses of technical, scientific and transferrable skills, active participation to public scientific events, and an intense inter-sectoral networking exchange plan.
Marine organisms have the capacity to produce a variety of biologically potent natural products, including antibiotic and anticancer compounds. MarPipe aims at further development of antimicrobial and anticancer lead compounds originating from a previous EU project (PharmaSea), and will also explore the bioactivity of deep-sea samples (5000m) collected during the recent Eurofleet-2 project in the sub-Antarctic. The PhD students will thus be involved in all phases of the drug discovery pipeline, from isolation of new microbial strains to pre-clinical development of lead compounds. Importantly, they will also be trained to overcome existing bottlenecks in the field, e.g. low yields and low chemodiversity, isolation of known compounds, toxicity of compounds.
The discovery rates of new bioactive antimicrobial and anticancer molecules will be enhanced through 11 PhD projects that cover all phases of the biodiscovery pipeline. As a final outcome of the project, we envisage the creation of a marine biodiscovery start-up company, which will include most of the MarPipe partners. The scientists of the future will be trained to become conscious about the socio-economic and policy context of their work, since several specific MarPipe PhD projects focus on legal, policy, innovation and entrepreneurship themes.
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Coordinator

CONSIGLIO NAZIONALE DELLE RICERCHE

Address

Piazzale Aldo Moro 7
00185 Roma

Italy

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 258 061,32

Participants (11)

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STAZIONE ZOOLOGICA ANTON DOHRN

Italy

EU Contribution

€ 258 061,32

UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET

Norway

EU Contribution

€ 286 275,24

THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN

United Kingdom

EU Contribution

€ 273 287,88

HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL

Germany

EU Contribution

€ 249 216,48

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgium

EU Contribution

€ 250 560

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK

Ireland

EU Contribution

€ 265 674,60

ECOAST

Belgium

EU Contribution

€ 250 560

FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA

Spain

EU Contribution

€ 247 872,96

MICRODISH BV

Netherlands

CONSORZIO ITALBIOTEC

Italy

EU Contribution

€ 258 061,32

WAGENINGEN UNIVERSITY

Netherlands

EU Contribution

€ 255 374,28

Partners (1)

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ALTA RICERCA E SVILUPPO IN BIOTECNOLOGIE SRLU

Project information

Grant agreement ID: 721421

Status

Ongoing project

  • Start date

    1 November 2016

  • End date

    31 October 2020

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 2 853 005,40

  • EU contribution

    € 2 853 005,40

Coordinated by:

CONSIGLIO NAZIONALE DELLE RICERCHE

Italy