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Multidisciplinary European training network for development of personalized anti-infective medical devices combining printing technologies and antimicrobial functionality

Objective

According to ECDC, over 4 million healthcare-associated infections in the EU cause 37,000 deaths and cost EUR 7 billion/year. Half of them are related to medical devices (i.e., catheters, implants) and 80% of these are related to bacterial biofilms. A recent EC report highlighted the medical device sector’s role in driving EU economic growth, employing 500k people in 25k companies (80% are SMEs) with annual sales of EUR 85 billion. The strategy to prevent medical device-infections is alteration of the device’s surface with antimicrobials. However, current antimicrobial surfaces don’t control bacterial growth in tissue surrounding implants, and only Sterilex® has received regulatory approval in the US as anti-biofilm agent. Participants in this proposal have earlier demonstrated a dramatic in vitro inhibition of biofilm formation by 3D-printing surfaces with antibiotics incorporated into the carrier polymers. This discovery opens new possibilities for printed medical devices that better resist biofilms. Our objective is to set-up a new European education platform to guide and inspire young researchers in the intersectoral exploration of innovative routes to counteract microbial biofilms by fabricating anti-infective, tailored, 3D-printed medical devices. Current opportunities for young researchers to receive an structured, inter-sectoral and up-to-date education on personalized medicine and medical devices are marginal, and to our knowledge PRINT-AID is the first ETN set up for this purpose. State-of-the-art printing technologies will be combined with in vitro and in vivo biofilm models and novel tools for data integration/standardization. Doctoral training will be performed within a high-quality network of 12 participants (5 industrial) from the EU and US. It will include online and face-to-face courses taught by researchers with academic and industrial expertise in biofilms, 3D-printing research, antimicrobials, material science, and drug development.

Field of science

  • /natural sciences/biological sciences/microbiology/bacteriology
  • /natural sciences/chemical sciences/polymer science
  • /medical and health sciences/medical biotechnology/medical bioproducts/implants

Call for proposal

H2020-MSCA-ITN-2016
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

HELSINGIN YLIOPISTO
Address
Yliopistonkatu 3
00014 Helsingin Yliopisto
Finland
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 538 290,72

Participants (8)

UNIVERSITEIT GENT
Belgium
EU contribution
€ 250 560
Address
Sint Pietersnieuwstraat 25
9000 Gent
Activity type
Higher or Secondary Education Establishments
POLITECHNIKA WARSZAWSKA
Poland
EU contribution
€ 224 137,44
Address
Plac Politechniki 1
00 661 Warszawa
Activity type
Higher or Secondary Education Establishments
VOXDALE BVBA
Belgium
EU contribution
€ 250 560
Address
Bijkhoevelaan 32C
2110 Wijnegem
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITEIT ANTWERPEN
Belgium
EU contribution
€ 250 560
Address
Prinsstraat 13
2000 Antwerpen
Activity type
Higher or Secondary Education Establishments
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM

Participation ended

Netherlands
EU contribution
€ 0
Address
Meibergdreef 15
1105AZ Amsterdam
Activity type
Higher or Secondary Education Establishments
APTUIT (VERONA) SRL
Italy
EU contribution
€ 258 061,32
Address
Via Alessandro Fleming 4
37135 Verona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSIDADE DO PORTO
Portugal
EU contribution
€ 238 356,36
Address
Praca Gomes Teixeira
4099 002 Porto
Activity type
Higher or Secondary Education Establishments
AMC MEDICAL RESEARCH BV
Netherlands
EU contribution
€ 255 374,28
Address
Meibergdreef 9
1105AZ Amsterdam Zuidoost
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)

Partners (4)

Montana State University Bozeman
United States
Address
Montana Hall 309
59717 Bozeman
Activity type
Higher or Secondary Education Establishments
MADAM THERAPEUTICS BV
Netherlands
Address
Kade 1
2435 NM Zevenhove
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
3DTECH OY
Finland
Address
Hyvoninkatu 1
24240 Salo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BioSurface Technologies Corporation
United States
Address
"421 West Griffin Drive #2"
59715 Bozeman
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)