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Training European Network: Metabolic Dysfunctions associated with Pharmacological Treatment of Schizophrenia

Training European Network: Metabolic Dysfunctions associated with Pharmacological Treatment of Schizophrenia

Objective

TREATMENT is a Marie Sklodowska Curie Innovative Training Network proposal directly addressing the need for high-level training and career paths in risk evaluation of drug induced metabolic dysfunctions, a relevant aspect, so far unexplored by traditional toxicology studies, but urgently needed to challenge current severe limitations of health care interventions in mental disorders. These patients require life-long medications that subsequently trigger metabolic diseases with a strong negative impact on their health and well-being. To achieve this, and improve adherence to treatments, we will evaluate how short-term antipsychotic drug responses impact long-term metabolic control to identify and validate biomarkers with clinically predictive value for targeting drug induced metabolic dysfunctions. This effort will have added commercial value by enabling the design of predictive marker kits for testing adverse secondary metabolic effects of drugs to be used in pharmacological and medical practice. TREATMENT will provide multidisciplinary knowledge, capabilities and tools to implement this ambitious strategy by the training of young scientists in a program that combines pharmacology, metabolism and mental health research with strategies for product and tool design and validation. Our ultimate goal is to empower the intersectorial and trans-national employability of young scientists across academic, public and private sectors to foster the development and implementation of personalized medicine tools that will provide effective treatment regimens for life long health-care interventions and decrease the risk for development of chronic metabolic diseases.
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Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Address

Calle Serrano 117
28006 Madrid

Spain

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 991 491,84

Participants (8)

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UPPSALA UNIVERSITET

Sweden

EU Contribution

€ 527 318,64

CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO

Portugal

EU Contribution

€ 476 712,72

THE HEBREW UNIVERSITY OF JERUSALEM

Israel

EU Contribution

€ 520 601,04

UNIVERZA V LJUBLJANI

Slovenia

EU Contribution

€ 234 997,56

NIMGENETICS, GENOMICA Y MEDICINA S.L.

Spain

EU Contribution

€ 247 872,96

BNML BEHAVIORAL & MOLECULAR LAB

Portugal

EU Contribution

€ 238 356,36

FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO LA PRINCESA

Spain

EU Contribution

€ 247 872,96

CELL STRESS DISCOVERIES LIMITED

Ireland

EU Contribution

€ 265 674,60

Partners (3)

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CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED M.P.

UNIVERSIDAD DE LLEIDA

ANAXOMICS BIOTECH, S.L.

Project information

Grant agreement ID: 721236

Status

Ongoing project

  • Start date

    1 January 2017

  • End date

    31 December 2020

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 750 898,68

  • EU contribution

    € 3 750 898,68

Coordinated by:

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS

Spain