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Optomechanics for Virology

Objective

Viral infections diagnosis demands novel, cheaper and rapid technologies to overcome present constraints. Current gold standard for diagnosis of viral infections is based on pathogen-targeted nucleic acid identification; thus, it cannot discern infectious stages from latent ones and it demands time consuming adjustments when mutations occur or new emerging viruses are to be included in the diagnostic protocols. Lately, optomechanics has served to fundamental advancements in physics, from gravitational wave detection to the study of mechanical quantum ground states but it has not yet delivered its full applicability potential.
VIRUSCAN aims to apply frontier advancements in optomechanics to the biosensing and diagnostic fields and to create a new interdisciplinary research community with the goal to advance optomechanics, nanoelectromechanics, native mass spectrometry and biophysics towards clinical applications.
VIRUSCAN will provide a novel technology capable to identify viral particles and asses their infective potential through the characterization of two physical parameters: mass and stiffness. Stiffness of viral particles has been recently known to act as a regulator of their infectivity at different stages of the virus life cycle. In parallel, advancements in nanoelectromechanical systems have recently demonstrated that stiffness and mass information from nanoscale adsorbates can be disentangled. Targeting intrinsic physical properties of viral particles will allow developing an open platform that will tackle any virus and their mutations.
VIRUSCAN will have impact at all levels by: providing a personalized treatment to the patients, reducing the use of not effective antibiotics, increasing safety in blood transfusions, allowing a quick and trustworthy response to emergency situations (e.g. recent EBOLA in West Africa and the ZIKA in Brazil), reducing the spread of viral infections, reducing costs per analysis and screening of a wide range of pathogens.

Call for proposal

FETPROACT-2016
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Address
Calle Serrano 117
28006 Madrid
Spain
Activity type
Research Organisations
EU contribution
€ 1 248 082,50

Participants (7)

UNIVERSITE DE PARIS
France
EU contribution
€ 856 486,25
Address
85 Bd Saint Germain
75006 Paris
Activity type
Higher or Secondary Education Establishments
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO
Netherlands
EU contribution
€ 1 079 262,50
Address
Anna Van Buerenplein 1
2595 DA Den Haag
Activity type
Research Organisations
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
France
EU contribution
€ 1 098 870
Address
Rue Leblanc 25
75015 Paris 15
Activity type
Research Organisations
RIJKSUNIVERSITEIT GRONINGEN
Netherlands
EU contribution
€ 579 062,50
Address
Broerstraat 5
9712CP Groningen
Activity type
Higher or Secondary Education Establishments
HEINRICH-PETTE INSTITUT LEIBNIZ INSTITUT FUER EXPERIMENTELLE VIROLOGIE
Germany
EU contribution
€ 882 500
Address
Martinistrasse 52
20251 Hamburg
Activity type
Research Organisations
SERVICIO MADRILENO DE SALUD
Spain
EU contribution
€ 603 750
Address
Plaza Carlos Trias Bertran 7
28020 Madrid
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA
Greece
EU contribution
€ 800 572,50
Address
Patriarchou Grigoriou E Kai Neapoleos, Lefkippos Technology Park, Ncsr Demokritos, Building 27
153 41 Agia Paraskevi
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)