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Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe

Project information

Grant agreement ID: 721567

Status

Ongoing project

  • Start date

    1 February 2017

  • End date

    31 January 2021

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 163 687,92

  • EU contribution

    € 3 163 687,92

Coordinated by:

STICHTING VU

Netherlands

Objective

In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority.
This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology.

Coordinator

STICHTING VU

Address

De Boelelaan 1105
1081 Hv Amsterdam

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 510 748,56

Participants (9)

KING'S COLLEGE LONDON

United Kingdom

EU Contribution

€ 273 287,88

GOETEBORGS UNIVERSITET

Sweden

EU Contribution

€ 263 659,32

UNIVERSITY OF BRISTOL

United Kingdom

EU Contribution

€ 546 575,76

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Netherlands

EU Contribution

€ 255 374,28

KAROLINSKA INSTITUTET

Sweden

EU Contribution

€ 263 659,32

UNIVERSITEIT TWENTE

Netherlands

EU Contribution

€ 255 374,28

UNIVERSITA DEGLI STUDI DI CAGLIARI

Italy

EU Contribution

€ 258 061,32

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE

United Kingdom

EU Contribution

€ 273 287,88

JANSSEN-CILAG AKTIEBOLAG

Sweden

EU Contribution

€ 263 659,32

Project information

Grant agreement ID: 721567

Status

Ongoing project

  • Start date

    1 February 2017

  • End date

    31 January 2021

Funded under:

H2020-EU.1.3.1.

  • Overall budget:

    € 3 163 687,92

  • EU contribution

    € 3 163 687,92

Coordinated by:

STICHTING VU

Netherlands