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Early-life stressors and LifeCycle health

Early-life stressors and LifeCycle health

Objective

Early life is an important window of opportunity to improve health across the full lifecycle. European pregnancy and child cohort studies together offer an unique opportunity to identify a wide range of early life stressors linked with individual biological, developmental and health trajectory variations, and to the onset and evolution of non-communicable diseases. LIFECYCLE will establish the EuroCHILD Cohort Network, which brings together existing, successful pregnancy and child cohorts and biobanks, by developing a governance structure taking account of national and European ethical, legal and societal implications, a shared data-management platform and data-harmonization strategies. LIFECYCLE will enrich this EuroCHILD Cohort Network by generating new integrated data on early life stressors related to socio-economic, migration, urban environment and life-style determinants, and will capitalize on these data by performing hypothesis-driven research on early life stressors influencing cardio-metabolic, respiratory and mental health trajectories during the full lifecycle, and the underlying epigenetic mechanisms. LIFECYCLE will translate these results into recommendations for targeted strategies and personalized prediction models to improve health trajectories for current and future Europeans generations by optimizing their earliest phase of life. To strengthen this long-term collaboration, LIFECYCLE will organize yearly international meetings open to pregnancy and child cohort researchers, introduce a Fellowship Training Programme for exchange of junior researchers between European pregnancy or child cohorts, and develop e-learning modules for researchers performing life-course health studies. Ultimately, LIFECYCLE will lead to a unique sustainable EuroCHILD Cohort Network, and provide recommendations for targeted prevention strategies by identification of novel markers of early life stressors related to health trajectories throughout the lifecycle.
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Coordinator

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Address

Dr Molewaterplein 40
3015 Gd Rotterdam

Netherlands

Activity type

Higher or Secondary Education Establishments

EU Contribution

€ 2 650 921,22

Participants (17)

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FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA

Spain

EU Contribution

€ 730 441,25

UNIVERSITA DEGLI STUDI DI TORINO

Italy

EU Contribution

€ 551 183,75

UNIVERSITY OF SOUTHAMPTON

United Kingdom

EU Contribution

€ 513 121,25

UNIVERSITY OF BRISTOL

United Kingdom

EU Contribution

€ 764 022,50

KOBENHAVNS UNIVERSITET

Denmark

EU Contribution

€ 617 352,50

BRADFORD TEACHING HOSPITALS NHS FOUNDATION TRUST

United Kingdom

EU Contribution

€ 479 281,25

ACADEMISCH ZIEKENHUIS GRONINGEN

Netherlands

EU Contribution

€ 702 708,75

PANEPISTIMIO KRITIS

Greece

EU Contribution

€ 401 500

FOLKEHELSEINSTITUTTET

Norway

EU Contribution

€ 535 386,25

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

EU Contribution

€ 342 920,84

OULUN YLIOPISTO

Finland

EU Contribution

€ 616 408,75

SAMFUNDET FOLKHALSAN I SVENSKA FINLAND RF

Finland

EU Contribution

€ 219 011,25

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

Germany

EU Contribution

€ 566 958,75

STICHTING VU

Netherlands

EU Contribution

€ 147 552,50

SLIMMERE ZORG BV

Netherlands

EU Contribution

€ 41 930,03

Concentris Research Management GmbH

Germany

EU Contribution

€ 76 901,25

THE UNIVERSITY OF WESTERN AUSTRALIA

Australia

Project information

Grant agreement ID: 733206

Status

Ongoing project

  • Start date

    1 January 2017

  • End date

    31 December 2021

Funded under:

H2020-EU.3.1.1.

  • Overall budget:

    € 10 414 945,84

  • EU contribution

    € 9 957 602,09

Coordinated by:

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Netherlands