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A global alliance for Zika virus control and prevention

Objective

"ZIKAlliance is a multidisciplinary project with a global ""One Health"" approach, built: on a multi-centric network of clinical cohorts in the Caribbean, Central & South America; research sites in countries where the virus has been or is currently circulating (Africa, Asia, Polynesia) or at risk for emergence (Reunion Island); a strong network of European and Brazilian clinical & basic research institutions; and multiple interfaces with other scientific and public health programmes. ZIKAlliance will addrees three key objectives relating to (i) impact of Zika virus (ZIKV) infection during pregnancy and short & medium term effects on newborns, (ii) associated natural history of ZIKV infection in humans and their environment in the context of other circulating arboviruses and (iii) building the overall capacity for preparedness research for future epidemic threats in Latin America & the Caribbean. The project will take advantage of large standardised clinical cohorts of pregnant women and febrile patients in regions of Latin America and the Caribbean were the virus is circulating, expanding a preexisting network established by the IDAMS EU project. I will also benefit of a very strong expertise in basic and environmental sciences, with access to both field work and sophisticated technological infrastructures to characterise virus replication and physiopathology mechanisms. To meet its 3 key objectives, the scientific project has been organised in 9 work packages, with WP2/3 dedicated to clinical research (cohorts, clinical biology, epidemiology & modeling), WP3/4 to basic research (virology & antivirals, pathophysiology & animal models), WP5/6 to environmental research (animal reservoirs, vectors & vector control) , WP7/8 to social sciences & communication, and WP9 to management. The broad consortium set-up allow gathering the necessary expertise for an actual interdisciplinary approach, and operating in a range of countries with contrasting ZIKV epidemiological status."
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Coordinator

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

Address

Rue De Tolbiac 101
75654 Paris

France

Activity type

Research Organisations

EU Contribution

€ 1 798 873

Participants (55)

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UNIVERSITATSKLINIKUM HEIDELBERG

Germany

EU Contribution

€ 2 252 950

FUNDACAO OSWALDO CRUZ

Brazil

EU Contribution

€ 657 400

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

Netherlands

EU Contribution

€ 634 867

ACADEMISCH ZIEKENHUIS LEIDEN

Netherlands

EU Contribution

€ 194 696

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgium

EU Contribution

€ 506 750

UNIVERSITATSKLINIKUM BONN

Germany

EU Contribution

€ 104 125

INSTITUT PASTEUR

France

EU Contribution

€ 830 125

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

United Kingdom

EU Contribution

€ 494 320

INSERM - TRANSFERT SA

France

EU Contribution

€ 312 500

INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT

France

EU Contribution

€ 216 600

FUNDACAO BAHIANA DE INFECTOLOGIA

Brazil

EU Contribution

€ 70 481

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

France

EU Contribution

€ 288 882,50

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

France

EU Contribution

€ 87 487,50

LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER

United Kingdom

EU Contribution

€ 380 625

UNIVERSIDADE NOVA DE LISBOA

Portugal

EU Contribution

€ 102 995

INSTITUTO DE HIGIENE E MEDICINA TROPICAL

Portugal

UNIVERSITE D'AIX MARSEILLE

France

EU Contribution

€ 131 958

FOLKEHELSEINSTITUTTET

Norway

EU Contribution

€ 22 000

UNIVERSITA DEGLI STUDI DI SIENA

Italy

EU Contribution

€ 65 000

INSTITUTO NACIONAL DE SALUD PUBLICA

Mexico

INSTITUTO MEXICANO DEL SEGURO SOCIAL

Mexico

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS

Netherlands

EU Contribution

€ 79 750

ACADEMISCH ZIEKENHUIS GRONINGEN

Netherlands

EU Contribution

€ 48 125

Universidad Industrial de Santander

Colombia

EU Contribution

€ 8 125

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

Germany

UNIVERSITE DE LIEGE

Belgium

EU Contribution

€ 250 000

UNIVERSIDADE FEDERAL DE MINAS GERAIS

Brazil

EU Contribution

€ 225 000

INSTITUT LOUIS MALARDE

French Polynesia

EU Contribution

€ 17 000

EIDGENOESSISCHES DEPARTEMENT DES INNERN

Switzerland

UNIVERSITAT DE BARCELONA

Spain

EU Contribution

€ 99 758

STIFTUNG TIERAERZTLICHE HOCHSCHULE HANNOVER

Germany

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Germany

EU Contribution

€ 75 000

JANSSEN PHARMACEUTICA NV

Belgium

EU Contribution

€ 98 000

AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL

France

EU Contribution

€ 99 590

SOSECALI C LTDA

Ecuador

EU Contribution

€ 8 125

INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES

Spain

EU Contribution

€ 50 000

UNIVERSITAT ZURICH

Switzerland

UNIVERSITY OF GLASGOW

United Kingdom

EU Contribution

€ 97 000

BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN

Germany

EU Contribution

€ 89 500

INSTITUTO DE MEDICINA TROPICAL PEDRO KOURI

Cuba

EU Contribution

€ 8 125

FONDAZIONE EDMUND MACH

Italy

EU Contribution

€ 76 875

UNIVERSITE LYON 1 CLAUDE BERNARD

France

EU Contribution

€ 99 758

UNIVERSITE RENNES II

France

EU Contribution

€ 75 000

UNIVERSIDADE FEDERAL DE GOIAS

Brazil

EU Contribution

€ 8 125

WAGENINGEN UNIVERSITY

Netherlands

EU Contribution

€ 45 000

FONDAZIONE PER L ISTITUTO DI RICERCA IN BIOMEDICINA

Switzerland

INSTITUT PASTEUR DU CAMBODGE FOUNDATION

Cambodia

EU Contribution

€ 57 000

INSTITUT PASTEUR DE DAKAR

Senegal

EU Contribution

€ 57 000

INSTITUT PASTEUR DE NOUVELLE-CALEDONIE

New Caledonia

EU Contribution

€ 30 000

INSTITUT PASTEUR OF SHANGHAI, CHINESE ACADEMY OF SCIENCES

China

FUNDACAO FACULDADE DE MEDICINA

Brazil

EU Contribution

€ 471 437

Laboratorio Nacional de Computacao Cientifica

Brazil

EU Contribution

€ 6 250

OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG

Germany

EU Contribution

€ 266 000

CHARITE - UNIVERSITAETSMEDIZIN BERLIN

Germany

EU Contribution

€ 336 531

UNIVERSIDAD PERUANA CAYETANO HEREDIA

Peru

EU Contribution

€ 29 500

Project information

Grant agreement ID: 734548

Status

Ongoing project

  • Start date

    1 October 2016

  • End date

    30 September 2020

Funded under:

H2020-EU.3.1.3.

  • Overall budget:

    € 15 684 925,99

  • EU contribution

    € 11 964 209

Coordinated by:

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France